Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 508 A 449 |
| Chain | Residue |
| A | LEU30 |
| A | ASP106 |
| A | LYS107 |
| A | ILE126 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | GOL455 |
| A | ASP32 |
| A | GLY34 |
| A | VAL69 |
| A | PRO70 |
| A | TYR71 |
| A | GLN73 |
| A | GLY74 |
| A | LYS75 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 450 |
| Chain | Residue |
| A | ARG235 |
| A | GLN326 |
| A | SER327 |
| A | SER328 |
| A | THR329 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 451 |
| Chain | Residue |
| A | ARG96 |
| A | ALA97 |
| A | ASN98 |
| A | GLU134 |
| A | SER139 |
| A | GLN143 |
| A | HOH478 |
| A | HOH739 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 452 |
| Chain | Residue |
| A | ARG205 |
| A | ARG205 |
| A | HOH535 |
| A | HOH688 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 453 |
| Chain | Residue |
| A | TYR51 |
| A | GLN53 |
| A | GLN55 |
| A | LYS218 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 454 |
| Chain | Residue |
| A | TYR68 |
| A | PRO70 |
| A | ARG128 |
| A | SER187 |
| A | LEU188 |
| A | TRP189 |
| A | HOH488 |
| A | HOH494 |
| A | HOH740 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 455 |
| Chain | Residue |
| A | GLN12 |
| A | GLY230 |
| A | 508449 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17425515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19011241","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
