Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 09D A 501 |
| Chain | Residue |
| A | LEU30 |
| A | TYR198 |
| A | ASP228 |
| A | GLY230 |
| A | HOH702 |
| A | HOH821 |
| A | ASP32 |
| A | GLY34 |
| A | TYR71 |
| A | THR72 |
| A | GLN73 |
| A | PHE108 |
| A | ILE126 |
| A | ARG128 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 502 |
| Chain | Residue |
| A | ARG96 |
| A | ASN98 |
| A | GLU134 |
| A | HOH715 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | TYR222 |
| A | TYR384 |
| A | HOH767 |
| A | HOH861 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 504 |
| Chain | Residue |
| A | GLY11 |
| A | GLN12 |
| A | GLY13 |
| A | SER229 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | ALA335 |
| A | HOH760 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 505 |
| Chain | Residue |
| A | ASP131 |
| A | HIS397 |
| A | HOH822 |
| A | HOH898 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 506 |
| Chain | Residue |
| A | GLU255 |
| A | TRP270 |
| A | ASP390 |
| A | HIS396 |
| A | HIS398 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP228 | |
| Chain | Residue | Details |
| A | LYS65 | |
| A | LYS214 | |
| A | LYS218 | |
| A | LYS224 | |
| A | LYS238 | |
| A | LYS239 | |
| A | LYS246 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN92 | |
| A | ASN111 | |
| A | ASN162 | |
| A | ASN293 | |
