Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 359 |
| Chain | Residue |
| A | ASN291 |
| A | HOH408 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 360 |
| Chain | Residue |
| A | PRO109 |
| A | CYS110 |
| A | LYS111 |
| A | TYR113 |
| A | ASN255 |
| A | LEU260 |
| A | LEU261 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 361 |
| Chain | Residue |
| A | ARG98 |
| A | ARG137 |
| A | ASP245 |
| A | SO4364 |
| A | HOH424 |
| A | HOH442 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 362 |
| Chain | Residue |
| A | ARG108 |
| A | ASP249 |
| A | ALA277 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 363 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 364 |
| Chain | Residue |
| A | ARG98 |
| A | ASN106 |
| A | ARG108 |
| A | SER263 |
| A | GLU275 |
| A | ALA277 |
| A | SO4361 |
| A | HOH442 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLFGDIlSDelAain.GSLGL |
| Chain | Residue | Details |
| A | ASN241-LEU260 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 31 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01033","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalysis","evidences":[{"source":"HAMAP-Rule","id":"MF_01033","evidenceCode":"ECO:0000255"}]} |
