3UCT

Structure of Mn2+-bound N-terminal domain of calmodulin in the presence of Zn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
B	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN A 100

Chain	Residue
A	ASP20
A	ASP22
A	ASP24
A	THR26
A	HOH91
A	HOH92
A	MN102

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 101

Chain	Residue
A	ASN60
A	THR62
A	HOH106
A	HOH123
A	ASP56
A	ASP58

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN A 102

Chain	Residue
A	ASP2
A	ASP22
A	ASP24
A	HOH92
A	MN100
A	HOH137
A	HOH138

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 103

Chain	Residue
A	PHE19
A	GLU31
A	HOH93
A	HOH94
A	HOH114

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 104

Chain	Residue
A	ASP64
A	GLU67

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN B 100

Chain	Residue
A	HOH110
B	ASP20
B	ASP22
B	ASP24
B	THR26
B	HOH85
B	ZN102

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 101

Chain	Residue
B	ASP56
B	ASP58
B	ASN60
B	THR62
B	HOH88
B	HOH89

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 102

Chain	Residue
A	GLU45
A	HOH110
B	ASP22
B	ASP24
B	MN100

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 103

Chain	Residue
B	ASP64
B	GLU67

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 104

Chain	Residue
B	ASP50
B	GLU54

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
A	ASP20-LEU32
A	ASP56-PHE68

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:1474585, ECO:0000269|PubMed:25441029, ECO:0000269|PubMed:27564677, ECO:0007744|PDB:1CLL, ECO:0007744|PDB:4UMO, ECO:0007744|PDB:4V0C, ECO:0007744|PDB:5J03

Chain	Residue	Details
A	ASP20
A	GLU67
B	ASP20
B	ASP22
B	ASP24
B	THR26
B	GLU31
B	ASP56
B	ASP58
B	ASN60
B	THR62
A	ASP22
B	GLU67
A	ASP24
A	THR26
A	GLU31
A	ASP56
A	ASP58
A	ASN60
A	THR62

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N-acetylalanine => ECO:0000269|PubMed:7093203, ECO:0000269|Ref.7, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712

Chain	Residue	Details
A	ALA1
B	ALA1

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS21
B	LYS21

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by CaMK4 => ECO:0000250|UniProtKB:P0DP29

Chain	Residue	Details
A	THR44
B	THR44

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62157

Chain	Residue	Details
A	LYS21
B	LYS21

---