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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

3U9P

Crystal Structure of Murine Siderocalin in Complex with an Fab Fragment

Functional Information from GO Data
ChainGOidnamespacecontents
C0002020molecular_functionprotease binding
C0002376biological_processimmune system process
C0005506molecular_functioniron ion binding
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005829cellular_componentcytosol
C0006811biological_processmonoatomic ion transport
C0006826biological_processiron ion transport
C0006915biological_processapoptotic process
C0006953biological_processacute-phase response
C0006979biological_processresponse to oxidative stress
C0007614biological_processshort-term memory
C0007616biological_processlong-term memory
C0009410biological_processresponse to xenobiotic stimulus
C0009615biological_processresponse to virus
C0009617biological_processresponse to bacterium
C0009635biological_processresponse to herbicide
C0009636biological_processresponse to toxic substance
C0009637biological_processresponse to blue light
C0009750biological_processresponse to fructose
C0010040biological_processresponse to iron(II) ion
C0010046biological_processresponse to mycotoxin
C0010595biological_processpositive regulation of endothelial cell migration
C0010628biological_processpositive regulation of gene expression
C0015891biological_processsiderophore transport
C0031346biological_processpositive regulation of cell projection organization
C0031410cellular_componentcytoplasmic vesicle
C0031667biological_processresponse to nutrient levels
C0031669biological_processcellular response to nutrient levels
C0032496biological_processresponse to lipopolysaccharide
C0036094molecular_functionsmall molecule binding
C0036295biological_processcellular response to increased oxygen levels
C0042742biological_processdefense response to bacterium
C0042802molecular_functionidentical protein binding
C0043065biological_processpositive regulation of apoptotic process
C0043525biological_processpositive regulation of neuron apoptotic process
C0045087biological_processinnate immune response
C0060205cellular_componentcytoplasmic vesicle lumen
C0070301biological_processcellular response to hydrogen peroxide
C0071222biological_processcellular response to lipopolysaccharide
C0071347biological_processcellular response to interleukin-1
C0071354biological_processcellular response to interleukin-6
C0071356biological_processcellular response to tumor necrosis factor
C0071456biological_processcellular response to hypoxia
C0071481biological_processcellular response to X-ray
C0097192biological_processextrinsic apoptotic signaling pathway in absence of ligand
C0110090biological_processpositive regulation of hippocampal neuron apoptotic process
C0110091biological_processnegative regulation of hippocampal neuron apoptotic process
C0120162biological_processpositive regulation of cold-induced thermogenesis
C0140315molecular_functioniron ion sequestering activity
C1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
C1903981molecular_functionenterobactin binding
C1904373biological_processresponse to kainic acid
C1904440biological_processpositive regulation of iron ion import across plasma membrane
C1904646biological_processcellular response to amyloid-beta
C1905956biological_processpositive regulation of endothelial tube morphogenesis
C1990090biological_processcellular response to nerve growth factor stimulus
C2000379biological_processpositive regulation of reactive oxygen species metabolic process
D0002020molecular_functionprotease binding
D0002376biological_processimmune system process
D0005506molecular_functioniron ion binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005829cellular_componentcytosol
D0006811biological_processmonoatomic ion transport
D0006826biological_processiron ion transport
D0006915biological_processapoptotic process
D0006953biological_processacute-phase response
D0006979biological_processresponse to oxidative stress
D0007614biological_processshort-term memory
D0007616biological_processlong-term memory
D0009410biological_processresponse to xenobiotic stimulus
D0009615biological_processresponse to virus
D0009617biological_processresponse to bacterium
D0009635biological_processresponse to herbicide
D0009636biological_processresponse to toxic substance
D0009637biological_processresponse to blue light
D0009750biological_processresponse to fructose
D0010040biological_processresponse to iron(II) ion
D0010046biological_processresponse to mycotoxin
D0010595biological_processpositive regulation of endothelial cell migration
D0010628biological_processpositive regulation of gene expression
D0015891biological_processsiderophore transport
D0031346biological_processpositive regulation of cell projection organization
D0031410cellular_componentcytoplasmic vesicle
D0031667biological_processresponse to nutrient levels
D0031669biological_processcellular response to nutrient levels
D0032496biological_processresponse to lipopolysaccharide
D0036094molecular_functionsmall molecule binding
D0036295biological_processcellular response to increased oxygen levels
D0042742biological_processdefense response to bacterium
D0042802molecular_functionidentical protein binding
D0043065biological_processpositive regulation of apoptotic process
D0043525biological_processpositive regulation of neuron apoptotic process
D0045087biological_processinnate immune response
D0060205cellular_componentcytoplasmic vesicle lumen
D0070301biological_processcellular response to hydrogen peroxide
D0071222biological_processcellular response to lipopolysaccharide
D0071347biological_processcellular response to interleukin-1
D0071354biological_processcellular response to interleukin-6
D0071356biological_processcellular response to tumor necrosis factor
D0071456biological_processcellular response to hypoxia
D0071481biological_processcellular response to X-ray
D0097192biological_processextrinsic apoptotic signaling pathway in absence of ligand
D0110090biological_processpositive regulation of hippocampal neuron apoptotic process
D0110091biological_processnegative regulation of hippocampal neuron apoptotic process
D0120162biological_processpositive regulation of cold-induced thermogenesis
D0140315molecular_functioniron ion sequestering activity
D1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
D1903981molecular_functionenterobactin binding
D1904373biological_processresponse to kainic acid
D1904440biological_processpositive regulation of iron ion import across plasma membrane
D1904646biological_processcellular response to amyloid-beta
D1905956biological_processpositive regulation of endothelial tube morphogenesis
D1990090biological_processcellular response to nerve growth factor stimulus
D2000379biological_processpositive regulation of reactive oxygen species metabolic process
Functional Information from PROSITE/UniProt
site_idPS00213
Number of Residues14
DetailsLIPOCALIN Lipocalin signature. DFRsdQFRGRWYVV
ChainResidueDetails
CASP15-VAL28
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEVVH
ChainResidueDetails
LTYR192-HIS198
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"P80188","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21911364","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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