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3U9P

Crystal Structure of Murine Siderocalin in Complex with an Fab Fragment

Functional Information from GO Data
ChainGOidnamespacecontents
C0002020molecular_functionprotease binding
C0005506molecular_functioniron ion binding
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005829cellular_componentcytosol
C0006826biological_processiron ion transport
C0006915biological_processapoptotic process
C0007614biological_processshort-term memory
C0007616biological_processlong-term memory
C0009410biological_processresponse to xenobiotic stimulus
C0009615biological_processresponse to virus
C0009617biological_processresponse to bacterium
C0009635biological_processresponse to herbicide
C0010595biological_processpositive regulation of endothelial cell migration
C0010628biological_processpositive regulation of gene expression
C0015891biological_processsiderophore transport
C0031346biological_processpositive regulation of cell projection organization
C0031410cellular_componentcytoplasmic vesicle
C0036094molecular_functionsmall molecule binding
C0042742biological_processdefense response to bacterium
C0042802molecular_functionidentical protein binding
C0043065biological_processpositive regulation of apoptotic process
C0043525biological_processpositive regulation of neuron apoptotic process
C0045087biological_processinnate immune response
C0060205cellular_componentcytoplasmic vesicle lumen
C0070301biological_processcellular response to hydrogen peroxide
C0097192biological_processextrinsic apoptotic signaling pathway in absence of ligand
C0110090biological_processpositive regulation of hippocampal neuron apoptotic process
C0110091biological_processnegative regulation of hippocampal neuron apoptotic process
C0120162biological_processpositive regulation of cold-induced thermogenesis
C0140315molecular_functioniron ion sequestering activity
C1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
C1903981molecular_functionenterobactin binding
C1904440biological_processpositive regulation of iron ion import across plasma membrane
C1905956biological_processpositive regulation of endothelial tube morphogenesis
C2000379biological_processpositive regulation of reactive oxygen species metabolic process
D0002020molecular_functionprotease binding
D0005506molecular_functioniron ion binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005829cellular_componentcytosol
D0006826biological_processiron ion transport
D0006915biological_processapoptotic process
D0007614biological_processshort-term memory
D0007616biological_processlong-term memory
D0009410biological_processresponse to xenobiotic stimulus
D0009615biological_processresponse to virus
D0009617biological_processresponse to bacterium
D0009635biological_processresponse to herbicide
D0010595biological_processpositive regulation of endothelial cell migration
D0010628biological_processpositive regulation of gene expression
D0015891biological_processsiderophore transport
D0031346biological_processpositive regulation of cell projection organization
D0031410cellular_componentcytoplasmic vesicle
D0036094molecular_functionsmall molecule binding
D0042742biological_processdefense response to bacterium
D0042802molecular_functionidentical protein binding
D0043065biological_processpositive regulation of apoptotic process
D0043525biological_processpositive regulation of neuron apoptotic process
D0045087biological_processinnate immune response
D0060205cellular_componentcytoplasmic vesicle lumen
D0070301biological_processcellular response to hydrogen peroxide
D0097192biological_processextrinsic apoptotic signaling pathway in absence of ligand
D0110090biological_processpositive regulation of hippocampal neuron apoptotic process
D0110091biological_processnegative regulation of hippocampal neuron apoptotic process
D0120162biological_processpositive regulation of cold-induced thermogenesis
D0140315molecular_functioniron ion sequestering activity
D1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
D1903981molecular_functionenterobactin binding
D1904440biological_processpositive regulation of iron ion import across plasma membrane
D1905956biological_processpositive regulation of endothelial tube morphogenesis
D2000379biological_processpositive regulation of reactive oxygen species metabolic process
Functional Information from PROSITE/UniProt
site_idPS00213
Number of Residues14
DetailsLIPOCALIN Lipocalin signature. DFRsdQFRGRWYVV
ChainResidueDetails
CASP15-VAL28

site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEVVH
ChainResidueDetails
LTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P80188
ChainResidueDetails
CTYR46
DTYR134
CTYR102
CLYS121
CLYS130
CTYR134
DTYR46
DTYR102
DLYS121
DLYS130

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Pyrrolidone carboxylic acid => ECO:0000250|UniProtKB:P80188
ChainResidueDetails
CGLN-5
DGLN-5

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
CASN55
DASN55

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21911364
ChainResidueDetails
CASN59
DASN59

223166

PDB entries from 2024-07-31

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