Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003746 | molecular_function | translation elongation factor activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006412 | biological_process | translation |
| A | 0006414 | biological_process | translational elongation |
| A | 0032045 | cellular_component | guanyl-nucleotide exchange factor complex |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GDP A 501 |
| Chain | Residue |
| A | HIS19 |
| A | ASP50 |
| A | ASN135 |
| A | LYS136 |
| A | ASP138 |
| A | MET139 |
| A | SER173 |
| A | LEU175 |
| A | HOH433 |
| A | MG503 |
| A | VAL20 |
| A | ASP21 |
| A | HIS22 |
| A | GLY23 |
| A | LYS24 |
| A | THR25 |
| A | THR26 |
| A | PHE46 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 503 |
| Chain | Residue |
| A | THR25 |
| A | ASP50 |
| A | HOH405 |
| A | HOH433 |
| A | GDP501 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR CHAIN B OF NVP-LFF571 |
| Chain | Residue |
| A | THR38 |
| A | TYR39 |
| A | PRO72 |
| A | GLU215 |
| A | ASP216 |
| A | PHE218 |
| A | THR228 |
| A | THR256 |
| A | GLY257 |
| A | GLU259 |
| A | PHE261 |
| A | ARG262 |
| A | ASN273 |
| A | VAL274 |
| A | GLY275 |
| A | LEU277 |
| A | LYS303 |
| A | HIS319 |
| A | THR320 |
| A | PRO321 |
| A | PHE323 |
| A | HOH407 |
| B | HOH13 |
| B | HOH18 |
| B | HOH87 |
Functional Information from PROSITE/UniProt
| site_id | PS00301 |
| Number of Residues | 16 |
| Details | G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNapeEKaRGITIntS |
| Chain | Residue | Details |
| A | ASP50-SER65 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP80 | |
| A | ASN135 | |
| B | MEN3 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: 3-hydroxyphenylalanine => ECO:0000250 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Thiazole-4-carboxylic acid (Ser-Cys) |
| Chain | Residue | Details |
| B | SER1 | |
| B | MH611 | |
| B | BB92 | |
| B | 7BB12 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Thiazole-4-carboxylic acid (Cys-Cys) |
| Chain | Residue | Details |
| B | BB99 | |
| B | BB910 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CROSSLNK: 5-methylthiazole-4-carboxylic acid (Asn-Cys) |
| Chain | Residue | Details |
| B | MEN3 | |
| B | BB64 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CROSSLNK: 5-(methoxymethyl)thiazole-4-carboxylic acid (Val-Cys) |
| Chain | Residue | Details |
| B | BB76 | |
| B | VAL5 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CROSSLNK: Thiazole-4-carboxylic acid (Phe-Cys) |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 535 |
| Chain | Residue | Details |
| A | ASP21 | electrostatic stabiliser |
| A | LYS24 | electrostatic stabiliser |
| A | THR25 | metal ligand |
| A | HIS84 | electrostatic stabiliser |
