Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0044423 | cellular_component | virion component |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003724 | molecular_function | RNA helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0044423 | cellular_component | virion component |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003724 | molecular_function | RNA helicase activity |
| D | 0005524 | molecular_function | ATP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 101 |
| Chain | Residue |
| A | TRP61 |
| A | GLU63 |
| B | ARG142 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 201 |
| Chain | Residue |
| B | ARG64 |
| C | GLU54 |
| C | LYS55 |
| D | HIS60 |
| D | ASN61 |
| D | HOH324 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 101 |
| Chain | Residue |
| D | PRO132 |
| D | GLY133 |
| D | HOH329 |
| E | ARG4 |
| E | HOH201 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 F 101 |
| Chain | Residue |
| B | PRO132 |
| B | GLY133 |
| D | ARG54 |
| D | HOH320 |
| F | ARG4 |
| F | OAR5 |
| F | HOH201 |
| F | HOH206 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR CHAIN E OF PEPTIDE OF (BEZ)(NLE)KR(OAR) |
| Chain | Residue |
| C | ASP81 |
| D | HIS51 |
| D | ASP129 |
| D | PHE130 |
| D | SER135 |
| D | TYR150 |
| D | GLY151 |
| D | ASN152 |
| D | GLY153 |
| D | TYR161 |
| E | SO4101 |
| F | BEZ1 |
| F | NLE2 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR CHAIN F OF PEPTIDE OF (BEZ)(NLE)KR(OAR) |
| Chain | Residue |
| A | GLY82 |
| A | MET84 |
| A | ARG85 |
| B | HIS51 |
| B | ASP129 |
| B | PHE130 |
| B | SER135 |
| B | GLY151 |
| B | ASN152 |
| B | GLY153 |
| B | TYR161 |
| B | HOH225 |
| D | ASP129 |
| D | GLY153 |
| D | TYR161 |
| E | ARG4 |
| E | OAR5 |
| F | SO4101 |
| F | HOH201 |
| F | HOH202 |
| F | HOH206 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"}]} |
3U1I
