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3U0F

The structure of Beta-ketoacyl synthase from Brucella melitensis bound to the fragment 7-hydroxycoumarin

Functional Information from GO Data
ChainGOidnamespacecontents
A0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006629biological_processlipid metabolic process
A0006631biological_processfatty acid metabolic process
A0006633biological_processfatty acid biosynthetic process
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL A 408
ChainResidue
AGLY69
AGLY71
ATHR72
AHOH644
AHOH675

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL A 409
ChainResidue
AMET267
AHOH479
AHOH546
AHOH718

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 410
ChainResidue
AASN294
APRO295
AGLU342
ASER388
AASN389
AHOH491

site_idAC4
Number of Residues12
DetailsBINDING SITE FOR RESIDUE 07L A 411
ChainResidue
AGLY105
AGLY106
ATHR109
AVAL132
AALA135
AMET136
AALA160
ACYS161
ALEU195
APHE199
ALEU335
AHOH653

Functional Information from PROSITE/UniProt
site_idPS00606
Number of Residues17
DetailsKS3_1 Ketosynthase family 3 (KS3) active site signature. GINysISsACATSnhCI
ChainResidueDetails
AGLY152-ILE168

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PDB entries from 2025-12-24

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