3TYU

Crystal Structure of Dihydropteroate synthetase with Product1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004156	molecular_function	dihydropteroate synthase activity
A	0005829	cellular_component	cytosol
A	0009396	biological_process	folic acid-containing compound biosynthetic process
A	0016740	molecular_function	transferase activity
A	0042558	biological_process	pteridine-containing compound metabolic process
A	0046654	biological_process	tetrahydrofolate biosynthetic process
A	0046656	biological_process	folic acid biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004156	molecular_function	dihydropteroate synthase activity
B	0005829	cellular_component	cytosol
B	0009396	biological_process	folic acid-containing compound biosynthetic process
B	0016740	molecular_function	transferase activity
B	0042558	biological_process	pteridine-containing compound metabolic process
B	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0046656	biological_process	folic acid biosynthetic process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE PT1 A 301

Chain	Residue
A	ASP96
A	SER222
A	ARG255
A	HOH294
A	HOH297
A	ASN115
A	ILE117
A	ASP185
A	GLY189
A	PHE190
A	LEU215
A	GLY217
A	LYS221

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PT1 B 302

Chain	Residue
B	ASP96
B	ASN115
B	ASP185
B	GLY189
B	PHE190
B	GLY217
B	LYS221
B	SER222
B	ARG255

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Functional Information from PROSITE/UniProt

site_id	PS00792
Number of Residues	16
Details	DHPS_1 Dihydropteroate synthase signature 1. VmGILNvTpDSFsDgG

Chain	Residue	Details
A	VAL17-GLY32

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site_id	PS00793
Number of Residues	14
Details	DHPS_2 Dihydropteroate synthase signature 2. GAtLIDIGGesTrP

Chain	Residue	Details
A	GLY51-PRO64

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