3TYG

Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0003823	molecular_function	antigen binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0016064	biological_process	immunoglobulin mediated immune response
L	0019814	cellular_component	immunoglobulin complex
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR206-HIS212

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17301785","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19965434","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NY7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IDX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IDY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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