3TX7
Crystal structure of LRH-1/beta-catenin complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE P6L B 100 |
| Chain | Residue |
| B | THR341 |
| B | GLN419 |
| B | ALA420 |
| B | GLY421 |
| B | THR423 |
| B | LEU424 |
| B | MET428 |
| B | ALA513 |
| B | TYR516 |
| B | LEU517 |
| B | LYS520 |
| B | PHE342 |
| B | MET345 |
| B | TRP382 |
| B | SER383 |
| B | LEU386 |
| B | ILE387 |
| B | HIS390 |
| B | ILE416 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15897460 |
| Chain | Residue | Details |
| B | LYS520 | |
| B | GLY421 | |
| B | TYR516 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000269|PubMed:20159957 |
| Chain | Residue | Details |
| B | LYS270 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by CDK5 => ECO:0000269|PubMed:17009320 |
| Chain | Residue | Details |
| A | SER246 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by PTK6 => ECO:0000269|PubMed:20026641 |
| Chain | Residue | Details |
| A | TYR331 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by SRC and PTK6 => ECO:0000269|PubMed:22056988, ECO:0000305|PubMed:20026641 |
| Chain | Residue | Details |
| A | TYR333 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER552 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18220336 |
| Chain | Residue | Details |
| A | THR556 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:Q02248 |
| Chain | Residue | Details |
| A | CYS619 |
