3TX7
Crystal structure of LRH-1/beta-catenin complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE P6L B 100 |
| Chain | Residue |
| B | THR341 |
| B | GLN419 |
| B | ALA420 |
| B | GLY421 |
| B | THR423 |
| B | LEU424 |
| B | MET428 |
| B | ALA513 |
| B | TYR516 |
| B | LEU517 |
| B | LYS520 |
| B | PHE342 |
| B | MET345 |
| B | TRP382 |
| B | SER383 |
| B | LEU386 |
| B | ILE387 |
| B | HIS390 |
| B | ILE416 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"ARM 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"ARM 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"ARM 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"ARM 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"ARM 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 28 |
| Details | Repeat: {"description":"ARM 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"ARM 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"ARM 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"ARM 9"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"ARM 11"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 22 |
| Details | Region: {"description":"Interaction with BCL9","evidences":[{"source":"PubMed","id":"17052462","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by CDK5","evidences":[{"source":"PubMed","id":"17009320","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by CDK5","evidences":[{"source":"PubMed","id":"17009320","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by PTK6","evidences":[{"source":"PubMed","id":"20026641","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by SRC and PTK6","evidences":[{"source":"PubMed","id":"22056988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20026641","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"Q02248","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15897460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22187462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22504882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26416531","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26553876","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ZDU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TX7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DOR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RWV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
