3TX4
Crystal Structure of Mutant (C354A) M. tuberculosis LD-transpeptidase type 2
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|PROSITE-ProRule:PRU01373, ECO:0000305|PubMed:23103390 |
| Chain | Residue | Details |
| A | HIS336 | |
| B | HIS336 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU01373, ECO:0000269|PubMed:23103390 |
| Chain | Residue | Details |
| A | ALA354 | |
| B | ALA354 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP232 | |
| A | GLU235 | |
| A | GLY236 | |
| B | ASP232 | |
| B | GLU235 | |
| B | GLY236 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | TYR318 | |
| A | SER331 | |
| A | ASN356 | |
| B | TYR318 | |
| B | SER331 | |
| B | ASN356 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Binds to carbapenem drug (covalent) => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA354 | |
| B | ALA354 |
