3TX1

X-ray crystal structure of Listeria monocytogenes EGD-e UDP-N-acetylenolpyruvylglucosamine reductase (MurB)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008360	biological_process	regulation of cell shape
A	0008762	molecular_function	UDP-N-acetylmuramate dehydrogenase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization
A	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	32
Details	BINDING SITE FOR RESIDUE FAD A 299

Chain	Residue
A	TYR24
A	ILE122
A	PRO123
A	GLY124
A	SER125
A	GLY127
A	GLY128
A	ALA129
A	HIS131
A	MET132
A	ALA134
A	ILE59
A	GLY135
A	ALA136
A	ARG170
A	TYR179
A	VAL181
A	ARG207
A	SER217
A	CYS218
A	GLY219
A	PHE256
A	GLY61
A	GOL300
A	SO4302
A	HOH310
A	ASN62
A	GLY63
A	SER64
A	ASN65
A	LEU66
A	LEU80

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 300

Chain	Residue
A	ARG170
A	SER220
A	GLU290
A	FAD299
A	HOH311
A	HOH316

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 301

Chain	Residue
A	ALA136
A	TYR137
A	GLY138
A	ARG170
A	ARG224
A	HOH316

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	HIS131
A	ALA175
A	LYS292
A	FAD299

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	SER220
A	PHE229
A	ALA230
A	GLY231
A	HIS253

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00037

Chain	Residue	Details
A	ARG170
A	GLU290

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00037

Chain	Residue	Details
A	SER220

---