Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3TUZ

Inward facing conformations of the MetNI methionine ABC transporter: CY5 SeMet soak crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006865	biological_process	amino acid transport
A	0015191	molecular_function	L-methionine transmembrane transporter activity
A	0016020	cellular_component	membrane
A	0048473	biological_process	D-methionine transmembrane transport
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	1902475	biological_process	L-alpha-amino acid transmembrane transport
A	1903692	biological_process	methionine import across plasma membrane
A	1990197	cellular_component	methionine-importing ABC transporter complex
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006865	biological_process	amino acid transport
B	0015191	molecular_function	L-methionine transmembrane transporter activity
B	0016020	cellular_component	membrane
B	0048473	biological_process	D-methionine transmembrane transport
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	1902475	biological_process	L-alpha-amino acid transmembrane transport
B	1903692	biological_process	methionine import across plasma membrane
B	1990197	cellular_component	methionine-importing ABC transporter complex
C	0003824	molecular_function	catalytic activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006865	biological_process	amino acid transport
C	0009276	cellular_component	Gram-negative-bacterium-type cell wall
C	0015191	molecular_function	L-methionine transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0033232	molecular_function	ABC-type D-methionine transporter activity
C	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
C	0048473	biological_process	D-methionine transmembrane transport
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	1902475	biological_process	L-alpha-amino acid transmembrane transport
C	1903692	biological_process	methionine import across plasma membrane
C	1990197	cellular_component	methionine-importing ABC transporter complex
D	0003824	molecular_function	catalytic activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006865	biological_process	amino acid transport
D	0009276	cellular_component	Gram-negative-bacterium-type cell wall
D	0015191	molecular_function	L-methionine transmembrane transporter activity
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0033232	molecular_function	ABC-type D-methionine transporter activity
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0048473	biological_process	D-methionine transmembrane transport
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	1902475	biological_process	L-alpha-amino acid transmembrane transport
D	1903692	biological_process	methionine import across plasma membrane
D	1990197	cellular_component	methionine-importing ABC transporter complex
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006865	biological_process	amino acid transport
E	0015191	molecular_function	L-methionine transmembrane transporter activity
E	0016020	cellular_component	membrane
E	0048473	biological_process	D-methionine transmembrane transport
E	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
E	0055085	biological_process	transmembrane transport
E	1902475	biological_process	L-alpha-amino acid transmembrane transport
E	1903692	biological_process	methionine import across plasma membrane
E	1990197	cellular_component	methionine-importing ABC transporter complex
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006865	biological_process	amino acid transport
F	0015191	molecular_function	L-methionine transmembrane transporter activity
F	0016020	cellular_component	membrane
F	0048473	biological_process	D-methionine transmembrane transport
F	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
F	0055085	biological_process	transmembrane transport
F	1902475	biological_process	L-alpha-amino acid transmembrane transport
F	1903692	biological_process	methionine import across plasma membrane
F	1990197	cellular_component	methionine-importing ABC transporter complex
G	0003824	molecular_function	catalytic activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006865	biological_process	amino acid transport
G	0009276	cellular_component	Gram-negative-bacterium-type cell wall
G	0015191	molecular_function	L-methionine transmembrane transporter activity
G	0016020	cellular_component	membrane
G	0016887	molecular_function	ATP hydrolysis activity
G	0033232	molecular_function	ABC-type D-methionine transporter activity
G	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
G	0048473	biological_process	D-methionine transmembrane transport
G	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
G	1902475	biological_process	L-alpha-amino acid transmembrane transport
G	1903692	biological_process	methionine import across plasma membrane
G	1990197	cellular_component	methionine-importing ABC transporter complex
H	0003824	molecular_function	catalytic activity
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006865	biological_process	amino acid transport
H	0009276	cellular_component	Gram-negative-bacterium-type cell wall
H	0015191	molecular_function	L-methionine transmembrane transporter activity
H	0016020	cellular_component	membrane
H	0016887	molecular_function	ATP hydrolysis activity
H	0033232	molecular_function	ABC-type D-methionine transporter activity
H	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
H	0048473	biological_process	D-methionine transmembrane transport
H	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
H	1902475	biological_process	L-alpha-amino acid transmembrane transport
H	1903692	biological_process	methionine import across plasma membrane
H	1990197	cellular_component	methionine-importing ABC transporter complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP C 2000

Chain	Residue
C	PHE11
C	GLN166
C	GLN13
C	ALA39
C	GLY41
C	ALA42
C	GLY43
C	LYS44
C	SER45
C	THR46

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ADP D 2000

Chain	Residue
D	PHE11
D	ILE18
D	ALA39
D	GLY41
D	ALA42
D	GLY43
D	LYS44
D	SER45
D	THR46

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ADP G 2000

Chain	Residue
G	GLY41
G	ALA42
G	GLY43
G	LYS44
G	SER45
G	THR46

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP H 2000

Chain	Residue
H	PHE11
H	GLN13
H	ALA39
H	SER40
H	GLY41
H	ALA42
H	GLY43
H	LYS44
H	SER45
H	THR46

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQKQRVAIARAL

Chain	Residue	Details
C	LEU141-LEU155

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269\|PubMed:22095702

Chain	Residue	Details
C	SER40
H	SER40
H	VAL278
H	ASN295
C	VAL278
C	ASN295
D	SER40
D	VAL278
D	ASN295
G	SER40
G	VAL278
G	ASN295

site_id	SWS_FT_FI2
Number of Residues	400
Details	TRANSMEM: Helical => ECO:0000255\|PROSITE-ProRule:PRU00441

Chain	Residue	Details
A	THR20-VAL40
B	ALA186-ALA206
E	THR20-VAL40
E	ALA58-PHE78
E	VAL81-ALA101
E	ILE152-LEU172
E	ALA186-ALA206
F	THR20-VAL40
F	ALA58-PHE78
F	VAL81-ALA101
F	ILE152-LEU172
A	ALA58-PHE78
F	ALA186-ALA206
A	VAL81-ALA101
A	ILE152-LEU172
A	ALA186-ALA206
B	THR20-VAL40
B	ALA58-PHE78
B	VAL81-ALA101
B	ILE152-LEU172

site_id	SWS_FT_FI3
Number of Residues	260
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	THR41-SER57
A	PRO102-THR151
B	THR41-SER57
B	PRO102-THR151
E	THR41-SER57
E	PRO102-THR151
F	THR41-SER57
F	PRO102-THR151

site_id	SWS_FT_FI4
Number of Residues	40
Details	TOPO_DOM: Cytoplasmic => ECO:0000269\|PubMed:15919996

Chain	Residue	Details
A	GLY207-LYS217
B	GLY207-LYS217
E	GLY207-LYS217
F	GLY207-LYS217

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)