3TUR
Crystal Structure of M. tuberculosis LD-transpeptidase type 2 complexed with a peptidoglycan fragment
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE 0JC A 501 |
| Chain | Residue |
| A | GLY346 |
| A | HIS347 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 0JC A 502 |
| Chain | Residue |
| A | MET157 |
| A | ALA171 |
| A | ARG173 |
| A | ARG209 |
| A | TYR330 |
| A | HOH737 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 0JC A 503 |
| Chain | Residue |
| A | GLU235 |
| A | MET237 |
| A | HIS150 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 0JC A 504 |
| Chain | Residue |
| A | GLU213 |
| A | HIS214 |
| A | PHE215 |
| A | ILE291 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DGL A 505 |
| Chain | Residue |
| A | TYR318 |
| A | THR320 |
| A | TRP340 |
| A | HIS352 |
| A | 6CL506 |
| A | HOH645 |
| A | HOH738 |
| B | THR320 |
| B | TRP340 |
| B | HIS352 |
| B | HOH605 |
| site_id | AC6 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE 6CL A 506 |
| Chain | Residue |
| A | TYR318 |
| A | SER331 |
| A | GLY332 |
| A | HIS336 |
| A | TRP340 |
| A | SER351 |
| A | HIS352 |
| A | GLY353 |
| A | CYS354 |
| A | ASN356 |
| A | DGL505 |
| A | HOH614 |
| A | HOH659 |
| A | HOH680 |
| A | HOH828 |
| B | TYR318 |
| B | SER331 |
| B | GLY332 |
| B | HIS336 |
| B | TRP340 |
| B | SER351 |
| B | HIS352 |
| B | GLY353 |
| B | CYS354 |
| B | ASN356 |
| B | HOH836 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PT B 501 |
| Chain | Residue |
| B | MET237 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 0JC B 502 |
| Chain | Residue |
| B | GLY346 |
| B | HIS347 |
| B | HOH718 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 0JC B 503 |
| Chain | Residue |
| B | GLU213 |
| B | HIS214 |
| B | PHE215 |
| B | HOH624 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 0JC B 504 |
| Chain | Residue |
| B | MET157 |
| B | ALA171 |
| B | ARG173 |
| B | ARG209 |
| B | TYR330 |
| B | HOH623 |
| B | HOH782 |
| B | HOH838 |
| B | HOH841 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE 0JC B 505 |
| Chain | Residue |
| B | MET153 |
| B | GLU240 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 250 |
| Details | Domain: {"description":"L,D-TPase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23103390","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23103390","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Binds to carbapenem drug (covalent)","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
