Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000165 | biological_process | MAPK cascade |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0004705 | molecular_function | JUN kinase activity |
A | 0004707 | molecular_function | MAP kinase activity |
A | 0004708 | molecular_function | MAP kinase kinase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0005829 | cellular_component | cytosol |
A | 0005886 | cellular_component | plasma membrane |
A | 0006468 | biological_process | protein phosphorylation |
A | 0007165 | biological_process | signal transduction |
A | 0007254 | biological_process | JNK cascade |
A | 0009416 | biological_process | response to light stimulus |
A | 0016020 | cellular_component | membrane |
A | 0016310 | biological_process | phosphorylation |
A | 0033554 | biological_process | cellular response to stress |
A | 0038095 | biological_process | Fc-epsilon receptor signaling pathway |
A | 0042752 | biological_process | regulation of circadian rhythm |
A | 0048511 | biological_process | rhythmic process |
A | 0090398 | biological_process | cellular senescence |
A | 0106310 | molecular_function | protein serine kinase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE JBI A 465 |
Chain | Residue |
A | GLY71 |
A | GLN155 |
A | VAL196 |
A | LEU206 |
A | HOH495 |
A | VAL78 |
A | ALA91 |
A | LYS93 |
A | ILE124 |
A | MET146 |
A | GLU147 |
A | MET149 |
A | ASN152 |
Functional Information from PROSITE/UniProt
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpsNIVV |
Chain | Residue | Details |
A | ILE185-VAL197 | |
site_id | PS01351 |
Number of Residues | 103 |
Details | MAPK MAP kinase signature. FqnqthakrayRElvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyllyqmlcgikhlhsagiih..........RDlKpsnivvksdC |
Chain | Residue | Details |
A | PHE99-CYS201 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | ASP189 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
A | ILE70 | |
A | LYS93 | |
Chain | Residue | Details |
A | THR221 | |
Chain | Residue | Details |
A | TYR223 | |
Chain | Residue | Details |
A | CYS462 | |
A | CYS463 | |