3TSM
Crystal structure of Indole-3-glycerol phosphate synthase from Brucella melitensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| A | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| A | 0006568 | biological_process | L-tryptophan metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0000162 | biological_process | L-tryptophan biosynthetic process |
| B | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| B | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| B | 0006568 | biological_process | L-tryptophan metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 271 |
| Chain | Residue |
| A | ARG121 |
| A | ASP123 |
| A | GLN130 |
| A | GLU133 |
| A | HOH288 |
| B | LYS13 |
| B | GLU16 |
| B | ALA20 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 271 |
| Chain | Residue |
| A | GLU16 |
| A | ALA20 |
| B | ARG121 |
| B | ASP123 |
| B | GLN130 |
| B | GLU133 |
| B | HOH339 |
| A | LYS13 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 269 |
| Chain | Residue |
| B | LYS62 |
| B | ARG194 |
| B | ILE244 |
| B | GLY245 |
| B | GLU246 |
| B | HOH309 |
| B | HOH319 |
| B | HOH325 |
| B | HOH363 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 276 |
| Chain | Residue |
| A | GLU229 |
| B | GLY53 |
| B | LEU232 |
| B | GLU235 |
| B | HOH360 |
Functional Information from PROSITE/UniProt
| site_id | PS00614 |
| Number of Residues | 19 |
| Details | IGPS Indole-3-glycerol phosphate synthase signature. LIaEIKKASPSkglirpdF |
| Chain | Residue | Details |
| A | LEU57-PHE75 |
