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3TR5

Structure of a peptide chain release factor 3 (prfC) from Coxiella burnetii

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006412biological_processtranslation
A0006415biological_processtranslational termination
A0006449biological_processregulation of translational termination
A0016149molecular_functiontranslation release factor activity, codon specific
A0016150molecular_functiontranslation release factor activity, codon nonspecific
A0097216molecular_functionguanosine tetraphosphate binding
B0000166molecular_functionnucleotide binding
B0003924molecular_functionGTPase activity
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006412biological_processtranslation
B0006415biological_processtranslational termination
B0006449biological_processregulation of translational termination
B0016149molecular_functiontranslation release factor activity, codon specific
B0016150molecular_functiontranslation release factor activity, codon nonspecific
B0097216molecular_functionguanosine tetraphosphate binding
C0000166molecular_functionnucleotide binding
C0003924molecular_functionGTPase activity
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006412biological_processtranslation
C0006415biological_processtranslational termination
C0006449biological_processregulation of translational termination
C0016149molecular_functiontranslation release factor activity, codon specific
C0016150molecular_functiontranslation release factor activity, codon nonspecific
C0097216molecular_functionguanosine tetraphosphate binding
D0000166molecular_functionnucleotide binding
D0003924molecular_functionGTPase activity
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006412biological_processtranslation
D0006415biological_processtranslational termination
D0006449biological_processregulation of translational termination
D0016149molecular_functiontranslation release factor activity, codon specific
D0016150molecular_functiontranslation release factor activity, codon nonspecific
D0097216molecular_functionguanosine tetraphosphate binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA A 526
ChainResidue
AGLN370
AGLN414
AGLU417
AHOH730

site_idAC2
Number of Residues19
DetailsBINDING SITE FOR RESIDUE GDP A 527
ChainResidue
ATHR25
AHIS89
AASN139
ALYS140
AASP142
AARG143
ASER254
AALA255
AILE256
AHOH533
AHOH558
AHOH629
AHOH650
AHOH778
AASP20
AALA21
AGLY22
ALYS23
ATHR24

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE CA B 526
ChainResidue
BGLN370
BGLN414
BGLU417
BHOH645
BHOH1130
BHOH1158
BHOH1217

site_idAC4
Number of Residues17
DetailsBINDING SITE FOR RESIDUE GDP B 527
ChainResidue
BASP20
BALA21
BGLY22
BLYS23
BTHR24
BTHR25
BHIS89
BASN139
BLYS140
BASP142
BARG143
BSER254
BALA255
BILE256
BHOH610
BHOH620
BHOH1129

site_idAC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA C 526
ChainResidue
CGLN370
CGLN414
CGLU417
CHOH613
CHOH865
CHOH1032

site_idAC6
Number of Residues16
DetailsBINDING SITE FOR RESIDUE GDP C 527
ChainResidue
CASP20
CALA21
CGLY22
CLYS23
CTHR24
CTHR25
CHIS89
CASN139
CLYS140
CASP142
CARG143
CSER254
CALA255
CILE256
CHOH545
CHOH757

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA D 526
ChainResidue
DGLN370
DGLN414
DGLU417
DHOH707

site_idAC8
Number of Residues18
DetailsBINDING SITE FOR RESIDUE GDP D 527
ChainResidue
DASP20
DALA21
DGLY22
DLYS23
DTHR24
DTHR25
DHIS89
DASN139
DLYS140
DASP142
DSER254
DALA255
DILE256
DHOH584
DHOH640
DHOH696
DHOH723
DHOH1051

Functional Information from PROSITE/UniProt
site_idPS00301
Number of Residues16
DetailsG_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DWmelEKqRGISVttS
ChainResidueDetails
AASP55-SER70

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues44
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00072","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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