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3TQ4

Crystal structure of M-PMV dUTPase with a mixed population of substrate (dUPNPP) and post-inversion product (dUMP) in the active sites

Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE UMP A 777
ChainResidue
AILE76
AILE102
ALYS103
AMET105
AGLN123
AMG153
AHOH156
AHOH157
AHOH242
AHOH246
AARG79
ASER80
AGLY92
AVAL93
AILE94
AASP95
ATYR98
AGLU101

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 153
ChainResidue
ADUP154
AHOH191
AHOH246
AHOH247
AUMP777

site_idAC3
Number of Residues19
DetailsBINDING SITE FOR RESIDUE DUP A 154
ChainResidue
AARG79
ASER80
ASER81
AGLY92
AVAL93
AILE94
AASP95
ATYR98
ALYS103
AMET105
AGLN123
AMG153
AHOH156
AHOH157
AHOH191
AHOH242
AHOH246
AHOH247
AHOH254

site_idAC4
Number of Residues11
DetailsBINDING SITE FOR RESIDUE TRS A 155
ChainResidue
AGLN88
AGLN88
AGLN88
AVAL89
AVAL89
AVAL89
ATYR90
ATYR90
APRO91
APRO91
APRO91

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Cleavage; by viral protease => ECO:0000269|PubMed:9636364
ChainResidueDetails
ATYR152

226707

PDB entries from 2024-10-30

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