3TPT
Structure of HipA(D309Q) bound to ADP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0000976 | molecular_function | transcription cis-regulatory region binding |
A | 0001217 | molecular_function | DNA-binding transcription repressor activity |
A | 0003677 | molecular_function | DNA binding |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005829 | cellular_component | cytosol |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0022611 | biological_process | dormancy process |
A | 0032993 | cellular_component | protein-DNA complex |
A | 0040008 | biological_process | regulation of growth |
A | 0043565 | molecular_function | sequence-specific DNA binding |
A | 0044010 | biological_process | single-species biofilm formation |
A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
A | 0046677 | biological_process | response to antibiotic |
A | 0106310 | molecular_function | protein serine kinase activity |
A | 0110001 | cellular_component | toxin-antitoxin complex |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0000976 | molecular_function | transcription cis-regulatory region binding |
B | 0001217 | molecular_function | DNA-binding transcription repressor activity |
B | 0003677 | molecular_function | DNA binding |
B | 0004674 | molecular_function | protein serine/threonine kinase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005524 | molecular_function | ATP binding |
B | 0005829 | cellular_component | cytosol |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0022611 | biological_process | dormancy process |
B | 0032993 | cellular_component | protein-DNA complex |
B | 0040008 | biological_process | regulation of growth |
B | 0043565 | molecular_function | sequence-specific DNA binding |
B | 0044010 | biological_process | single-species biofilm formation |
B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
B | 0046677 | biological_process | response to antibiotic |
B | 0106310 | molecular_function | protein serine kinase activity |
B | 0110001 | cellular_component | toxin-antitoxin complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE ADP A 500 |
Chain | Residue |
A | VAL98 |
A | VAL233 |
A | GLU234 |
A | ARG235 |
A | PHE236 |
A | ASP237 |
A | LYS313 |
A | ASN314 |
A | TYR331 |
A | ASP332 |
A | MG441 |
A | VAL151 |
A | HOH442 |
A | HOH465 |
A | HOH514 |
A | ALA152 |
A | GLY153 |
A | ALA154 |
A | GLN155 |
A | LYS157 |
A | LYS181 |
A | PRO218 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG A 441 |
Chain | Residue |
A | ASN314 |
A | ASP332 |
A | ADP500 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 833 |
Chain | Residue |
A | SER359 |
A | LYS363 |
A | ARG372 |
A | HIS373 |
A | HOH529 |
site_id | AC4 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE ADP B 501 |
Chain | Residue |
B | VAL98 |
B | VAL151 |
B | ALA152 |
B | GLY153 |
B | ALA154 |
B | GLN155 |
B | LYS157 |
B | ILE179 |
B | LYS181 |
B | PRO218 |
B | VAL233 |
B | GLU234 |
B | ARG235 |
B | PHE236 |
B | ASP237 |
B | GLN252 |
B | LYS313 |
B | ASN314 |
B | TYR331 |
B | ASP332 |
B | MG441 |
B | MG442 |
B | HOH444 |
B | HOH471 |
B | HOH514 |
B | HOH536 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG B 441 |
Chain | Residue |
B | GLN155 |
B | ASP332 |
B | ADP501 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 442 |
Chain | Residue |
B | ASN314 |
B | ASP332 |
B | HOH444 |
B | ADP501 |
B | HOH536 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 834 |
Chain | Residue |
B | ALA358 |
B | SER359 |
B | LYS363 |
B | ARG372 |
B | HIS373 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | DNA_BIND: DNA_BIND => ECO:0000269|PubMed:19150849 |
Chain | Residue | Details |
B | LYS379-ARG382 | |
A | LYS379-ARG382 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:17041039 |
Chain | Residue | Details |
A | GLN309 | |
B | GLN309 |
site_id | SWS_FT_FI3 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22999936, ECO:0007744|PDB:3DNT, ECO:0007744|PDB:3FBR, ECO:0007744|PDB:3HZI, ECO:0007744|PDB:3TPT |
Chain | Residue | Details |
A | HIS311 | |
A | TYR331 | |
B | ALA152 | |
B | GLU234 | |
B | HIS311 | |
B | TYR331 | |
A | ALA152 | |
A | GLU234 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22999936, ECO:0007744|PDB:3DNT, ECO:0007744|PDB:3HZI, ECO:0007744|PDB:3TPT |
Chain | Residue | Details |
A | LYS181 | |
B | LYS181 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine; by autocatalysis => ECO:0000269|PubMed:17041039, ECO:0000269|PubMed:22999936 |
Chain | Residue | Details |
A | SER150 | |
B | SER150 |