Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 394 |
| Chain | Residue |
| A | ARG61 |
| A | HOH682 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 395 |
| Chain | Residue |
| A | TYR51 |
| A | GLN53 |
| A | GLN55 |
| A | LYS218 |
| A | HOH660 |
| A | HOH718 |
| A | HOH776 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 396 |
| Chain | Residue |
| A | THR185 |
| A | GLY186 |
| A | HOH618 |
| A | HOH643 |
| A | HOH773 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 397 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 398 |
| Chain | Residue |
| A | URE406 |
| A | HOH600 |
| A | HOH640 |
| A | HOH782 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 399 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 400 |
| Chain | Residue |
| A | ARG96 |
| A | ASN98 |
| A | GLU134 |
| A | SER139 |
| A | GLN143 |
| A | HOH438 |
| A | HOH626 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | ARG194 |
| A | ASN385 |
| A | HOH506 |
| A | HOH607 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | SER22 |
| A | PRO23 |
| A | PRO24 |
| A | PRO91 |
| A | ASN92 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE URE A 403 |
| Chain | Residue |
| A | VAL67 |
| A | TYR68 |
| A | ARG128 |
| A | PRO129 |
| A | TRP189 |
| A | HOH598 |
| A | HOH712 |
| A | HOH748 |
| A | HOH762 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE URE A 404 |
| Chain | Residue |
| A | SER22 |
| A | SER58 |
| A | PRO147 |
| A | GLY177 |
| A | HOH509 |
| A | HOH765 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE URE A 405 |
| Chain | Residue |
| A | THR26 |
| A | PRO88 |
| A | PRO88 |
| A | HIS89 |
| A | HOH463 |
| A | HOH578 |
| A | HOH599 |
| A | HOH599 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE URE A 406 |
| Chain | Residue |
| A | ASP62 |
| A | SO4398 |
| A | HOH504 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP228 | |
| Chain | Residue | Details |
| A | LYS65 | |
| A | LYS214 | |
| A | LYS218 | |
| A | LYS224 | |
| A | LYS238 | |
| A | LYS239 | |
| A | LYS246 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN92 | |
| A | ASN111 | |
| A | ASN162 | |
| A | ASN293 | |
