Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 A 394 |
Chain | Residue |
A | ARG61 |
A | HOH682 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 395 |
Chain | Residue |
A | TYR51 |
A | GLN53 |
A | GLN55 |
A | LYS218 |
A | HOH660 |
A | HOH718 |
A | HOH776 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 396 |
Chain | Residue |
A | THR185 |
A | GLY186 |
A | HOH618 |
A | HOH643 |
A | HOH773 |
site_id | AC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE SO4 A 397 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 398 |
Chain | Residue |
A | URE406 |
A | HOH600 |
A | HOH640 |
A | HOH782 |
site_id | AC6 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE SO4 A 399 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 400 |
Chain | Residue |
A | ARG96 |
A | ASN98 |
A | GLU134 |
A | SER139 |
A | GLN143 |
A | HOH438 |
A | HOH626 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 401 |
Chain | Residue |
A | ARG194 |
A | ASN385 |
A | HOH506 |
A | HOH607 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL A 402 |
Chain | Residue |
A | SER22 |
A | PRO23 |
A | PRO24 |
A | PRO91 |
A | ASN92 |
site_id | BC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE URE A 403 |
Chain | Residue |
A | VAL67 |
A | TYR68 |
A | ARG128 |
A | PRO129 |
A | TRP189 |
A | HOH598 |
A | HOH712 |
A | HOH748 |
A | HOH762 |
site_id | BC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE URE A 404 |
Chain | Residue |
A | SER22 |
A | SER58 |
A | PRO147 |
A | GLY177 |
A | HOH509 |
A | HOH765 |
site_id | BC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE URE A 405 |
Chain | Residue |
A | THR26 |
A | PRO88 |
A | PRO88 |
A | HIS89 |
A | HOH463 |
A | HOH578 |
A | HOH599 |
A | HOH599 |
site_id | BC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE URE A 406 |
Chain | Residue |
A | ASP62 |
A | SO4398 |
A | HOH504 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP32 | |
A | ASP228 | |
Chain | Residue | Details |
A | LYS65 | |
A | LYS214 | |
A | LYS218 | |
A | LYS224 | |
A | LYS238 | |
A | LYS239 | |
A | LYS246 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN92 | |
A | ASN111 | |
A | ASN162 | |
A | ASN293 | |