3TNF

LidA from Legionella in complex with active Rab8a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 199

Chain	Residue
A	THR22
A	THR40
A	ASP63
A	THR64
A	GNP200

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site_id	AC2
Number of Residues	26
Details	BINDING SITE FOR RESIDUE GNP A 200

Chain	Residue
A	LYS21
A	THR22
A	CYS23
A	PHE33
A	ASN34
A	SER35
A	PHE37
A	SER39
A	THR40
A	GLY66
A	ASN121
A	LYS122
A	ASP124
A	VAL125
A	SER151
A	ALA152
A	LYS153
A	HOH180
A	HOH183
A	MG199
B	HOH62
B	TYR532
A	SER17
A	GLY18
A	VAL19
A	GLY20

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MPD A 1

Chain	Residue
A	ARG71
A	TRP102
A	ASN105

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPD B 2

Chain	Residue
B	LEU254
B	GLU259
B	LEU334
B	LYS335
B	ALA393
B	LEU394

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD B 3

Chain	Residue
B	GLY233
B	LEU236
B	GLU237
B	THR550
B	HIS553

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD A 177

Chain	Residue
A	TRP62
A	TYR77
A	ARG79
B	LEU406
B	ASN410

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Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKtcV

Chain	Residue	Details
A	LEU11-VAL24

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000305|PubMed:21378754, ECO:0000305|PubMed:27552051, ECO:0007744|PDB:3QBT, ECO:0007744|PDB:5SZI

Chain	Residue	Details
A	SER17
A	LYS153
A	GLY20
A	LYS21
A	CYS23
A	GLY66
A	ASN121
A	LYS122
A	ASP124
A	ALA152

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:27552051, ECO:0007744|PDB:5SZI

Chain	Residue	Details
A	GLY18
A	VAL19
A	SER35

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:21378754, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3QBT, ECO:0007744|PDB:5SZI

Chain	Residue	Details
A	THR22
A	THR40

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:21378754, ECO:0007744|PDB:3QBT

Chain	Residue	Details
A	SER39

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:21378754, ECO:0007744|PDB:3QBT

Chain	Residue	Details
A	ASP63

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by LRRK2 => ECO:0000269|PubMed:26824392, ECO:0000269|PubMed:29125462, ECO:0000269|PubMed:30209220, ECO:0000269|PubMed:30398148

Chain	Residue	Details
A	THR72

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