3TND

Crystal structure of Shigella flexneri VapBC toxin-antitoxin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0003677	molecular_function	DNA binding
C	0000287	molecular_function	magnesium ion binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004540	molecular_function	RNA nuclease activity
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0003677	molecular_function	DNA binding
E	0000287	molecular_function	magnesium ion binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004540	molecular_function	RNA nuclease activity
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
F	0003677	molecular_function	DNA binding
G	0000287	molecular_function	magnesium ion binding
G	0004518	molecular_function	nuclease activity
G	0004519	molecular_function	endonuclease activity
G	0004540	molecular_function	RNA nuclease activity
G	0016787	molecular_function	hydrolase activity
G	0046872	molecular_function	metal ion binding
H	0003677	molecular_function	DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 133

Chain	Residue
A	LYS49
A	HOH150
A	HOH170
B	GLU65

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA B 82

Chain	Residue
B	HOH121

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 83

Chain	Residue
B	ARG15
B	PRO17
B	LYS18
D	SER11

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA D 82

Chain	Residue
C	HOH149
D	GLN66
D	HOH124

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 83

Chain	Residue
B	SER11
D	ARG15
D	PRO17
D	LYS18

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 84

Chain	Residue
D	ARG15
F	THR3
F	THR4

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 133

Chain	Residue
E	ARG55
F	SER57
F	THR58

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 82

Chain	Residue
F	ARG15
F	PRO17
F	LYS18
F	LYS18

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 G 133

Chain	Residue
C	LEU126
G	GLY125
G	LEU126
G	HOH145

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 82

Chain	Residue
B	ARG15
F	ARG28
H	THR3
H	THR4
H	ARG15

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 83

Chain	Residue
F	SER11
H	ARG15
H	PRO17
H	LYS18

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 84

Chain	Residue
G	LYS49
H	ASN63
H	HOH99
H	HOH113

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 85

Chain	Residue
G	ARG55
H	HIS54
H	SER55
H	HOH114

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	504
Details	Domain: {"description":"PINc"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	168
Details	Domain: {"description":"SpoVT-AbrB","evidences":[{"source":"PROSITE-ProRule","id":"PRU01076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---