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3TN2

structure analysis of MIP1-beta P8A

Functional Information from GO Data
ChainGOidnamespacecontents
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006935biological_processchemotaxis
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007155biological_processcell adhesion
A0007163biological_processestablishment or maintenance of cell polarity
A0007165biological_processsignal transduction
A0007267biological_processcell-cell signaling
A0008009molecular_functionchemokine activity
A0009615biological_processresponse to virus
A0009636biological_processresponse to toxic substance
A0030335biological_processpositive regulation of cell migration
A0031726molecular_functionCCR1 chemokine receptor binding
A0031730molecular_functionCCR5 chemokine receptor binding
A0042802molecular_functionidentical protein binding
A0043922biological_processnegative regulation by host of viral transcription
A0048020molecular_functionCCR chemokine receptor binding
A0048245biological_processeosinophil chemotaxis
A0050850biological_processpositive regulation of calcium-mediated signaling
A0051928biological_processpositive regulation of calcium ion transport
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0070098biological_processchemokine-mediated signaling pathway
A2000503biological_processpositive regulation of natural killer cell chemotaxis
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE ZN A 69
ChainResidue
AASP27
AASP27
AHOH105
AHOH105
AHOH106
AHOH106
AHOH107
AHOH107

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 70
ChainResidue
AHOH74
AHOH75
AHOH108
AGLU61

site_idAC3
Number of Residues1
DetailsBINDING SITE FOR RESIDUE ZN A 71
ChainResidue
AGLU67

Functional Information from PROSITE/UniProt
site_idPS00472
Number of Residues42
DetailsSMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCFsytark..LprnfVvdYyetssl..Csqp.AVVFqtkrskqv.CA
ChainResidueDetails
ACYS11-ALA52

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PDB entries from 2024-07-24

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