3TLF
Crystal structure of an enoyl-CoA hydratase/isomerase from Mycobacterium paratuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006635 | biological_process | fatty acid beta-oxidation |
| A | 0016829 | molecular_function | lyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006635 | biological_process | fatty acid beta-oxidation |
| B | 0016829 | molecular_function | lyase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006635 | biological_process | fatty acid beta-oxidation |
| C | 0016829 | molecular_function | lyase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0006631 | biological_process | fatty acid metabolic process |
| D | 0006635 | biological_process | fatty acid beta-oxidation |
| D | 0016829 | molecular_function | lyase activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| E | 0006629 | biological_process | lipid metabolic process |
| E | 0006631 | biological_process | fatty acid metabolic process |
| E | 0006635 | biological_process | fatty acid beta-oxidation |
| E | 0016829 | molecular_function | lyase activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| F | 0006629 | biological_process | lipid metabolic process |
| F | 0006631 | biological_process | fatty acid metabolic process |
| F | 0006635 | biological_process | fatty acid beta-oxidation |
| F | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 271 |
| Chain | Residue |
| D | GLU176 |
| D | ARG182 |
| D | HOH285 |
| D | HOH298 |
| D | HOH306 |
| D | HOH318 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO E 271 |
| Chain | Residue |
| D | GLU176 |
| E | ARG201 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO E 272 |
| Chain | Residue |
| E | GLU176 |
| E | ARG182 |
| E | HOH283 |
| E | HOH299 |
| E | HOH327 |
| E | HOH407 |
| E | ARG168 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 271 |
| Chain | Residue |
| E | HIS175 |
| E | GLU176 |
| F | ARG201 |
| F | ILE208 |
| F | HOH849 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO F 272 |
| Chain | Residue |
| F | ILE165 |
| F | ARG168 |
| F | GLU176 |
| F | ARG182 |
| F | HOH287 |
| F | HOH292 |
| F | HOH299 |
| F | HOH301 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 271 |
| Chain | Residue |
| A | ARG168 |
| A | GLU176 |
| A | HOH288 |
| A | HOH308 |
| A | HOH592 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 271 |
| Chain | Residue |
| B | ARG168 |
| B | GLU176 |
| B | ARG182 |
| B | HOH286 |
| B | HOH308 |
| B | HOH316 |
| B | HOH390 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 271 |
| Chain | Residue |
| A | HOH287 |
| C | ILE165 |
| C | HOH288 |
| C | HOH297 |
| C | HOH410 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 272 |
| Chain | Residue |
| B | GLN96 |
| B | PRO101 |
| B | PHE102 |
| B | ARG103 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 272 |
| Chain | Residue |
| D | ARG201 |
| D | ILE208 |
| F | HIS175 |
| F | GLU176 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 272 |
| Chain | Residue |
| A | HIS44 |
| A | THR104 |
Functional Information from PROSITE/UniProt
| site_id | PS00166 |
| Number of Residues | 21 |
| Details | ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. LTaVNGiccGAGmdwvTtTDI |
| Chain | Residue | Details |
| A | LEU110-ILE130 |
