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3TKT

Crystal structure of CYP108D1 from Novosphingobium aromaticivorans DSM12444

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0006707biological_processcholesterol catabolic process
A0008395molecular_functionsteroid hydroxylase activity
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0036199molecular_functioncholest-4-en-3-one 26-monooxygenase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues25
DetailsBINDING SITE FOR RESIDUE HEM A 431
ChainResidue
ALEU104
ASER277
AVAL316
APHE319
AARG321
AALA371
APHE372
AGLY373
AALA374
AHIS377
ACYS379
AVAL105
AGLY381
AALA385
AHOH459
AHOH477
AHOH507
AHOH697
AHIS112
AARG116
ATHR266
AALA269
AGLY270
ATHR273
ATHR274

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGSHQCLG
ChainResidueDetails
APHE372-GLY381

224201

PDB entries from 2024-08-28

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