Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 264 |
| Chain | Residue |
| A | TYR61 |
| A | TYR220 |
| A | HOH271 |
| A | HOH273 |
| A | HOH283 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE CYZ A 266 |
| Chain | Residue |
| A | LYS104 |
| A | PRO105 |
| A | MET107 |
| A | SER108 |
| A | LEU239 |
| A | SER242 |
| A | LEU247 |
| A | ASP248 |
| A | HOH339 |
| A | HOH398 |
| A | HOH427 |
| A | HOH956 |
| A | HOH967 |
| B | ILE92 |
| B | SER217 |
| B | LYS218 |
| B | GLY219 |
| B | HOH329 |
| B | HOH364 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 265 |
| Chain | Residue |
| A | SER140 |
| A | LYS144 |
| A | ARG148 |
| A | HOH311 |
| A | HOH320 |
| A | HOH324 |
| A | HOH394 |
| A | HOH1016 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 267 |
| Chain | Residue |
| A | LYS82 |
| A | LYS116 |
| A | HOH371 |
| A | HOH903 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 268 |
| Chain | Residue |
| A | GLU97 |
| A | ASP101 |
| A | PHE102 |
| A | HOH575 |
| A | HOH748 |
| B | LYS104 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 269 |
| Chain | Residue |
| A | ARG148 |
| A | TRP159 |
| A | ARG163 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU B 264 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | GLU193 |
| B | TYR220 |
| B | HOH273 |
| B | HOH289 |
| B | HOH313 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE CYZ B 267 |
| Chain | Residue |
| A | ILE92 |
| A | SER217 |
| A | LYS218 |
| A | GLY219 |
| A | HOH387 |
| A | HOH390 |
| B | LYS104 |
| B | PRO105 |
| B | MET107 |
| B | SER108 |
| B | LEU239 |
| B | SER242 |
| B | LEU247 |
| B | ASP248 |
| B | HOH322 |
| B | HOH381 |
| B | HOH610 |
| B | HOH957 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 265 |
| Chain | Residue |
| B | SER140 |
| B | LYS144 |
| B | ARG148 |
| B | HOH308 |
| B | HOH320 |
| B | HOH401 |
| B | HOH489 |
| B | HOH1140 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 266 |
| Chain | Residue |
| A | LYS183 |
| B | ARG31 |
| B | HOH315 |
| B | HOH331 |
| B | HOH344 |
| B | HOH616 |
| B | HOH984 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 268 |
| Chain | Residue |
| A | LYS104 |
| B | GLU97 |
| B | ASP101 |
| B | PHE102 |
| B | HOH469 |
| B | HOH667 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 269 |
| Chain | Residue |
| A | LYS151 |
| B | LYS240 |
| B | GLN244 |
| B | HOH396 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 270 |
| Chain | Residue |
| B | ARG148 |
| B | TRP159 |
| B | ARG163 |
| B | HOH475 |
| B | HOH1060 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO89 | |
| B | SER142 | |
| B | THR143 | |
| B | GLU193 | |
| A | THR91 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| B | PRO89 | |
| B | THR91 | |
| B | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 | |
