3TK8
Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008666 | molecular_function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008666 | molecular_function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008666 | molecular_function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity |
| C | 0009085 | biological_process | lysine biosynthetic process |
| C | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0019877 | biological_process | diaminopimelate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 313 |
| Chain | Residue |
| A | ARG151 |
| A | ASN168 |
| A | SER187 |
| A | HOH406 |
| A | HOH940 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 314 |
| Chain | Residue |
| A | HOH341 |
| A | HOH428 |
| A | HOH475 |
| B | HOH352 |
| B | HOH369 |
| A | ASP180 |
| A | THR181 |
| A | GLY199 |
| A | HOH330 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 315 |
| Chain | Residue |
| A | GLN43 |
| A | VAL93 |
| A | HIS94 |
| A | GLN95 |
| A | TRP96 |
| A | HOH359 |
| A | HOH920 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 316 |
| Chain | Residue |
| A | THR133 |
| A | ALA134 |
| A | GLU135 |
| C | LYS280 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 317 |
| Chain | Residue |
| A | SER62 |
| A | ALA63 |
| A | ARG66 |
| A | HOH390 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 318 |
| Chain | Residue |
| A | ASN110 |
| A | LYS124 |
| A | HOH441 |
| A | HOH460 |
| A | HOH481 |
| A | HOH836 |
| C | ARG143 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 319 |
| Chain | Residue |
| A | GLY89 |
| A | ALA90 |
| A | TRP91 |
| A | ARG265 |
| A | HOH485 |
| A | HOH636 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 320 |
| Chain | Residue |
| A | ASN52 |
| A | LYS193 |
| A | HOH379 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 321 |
| Chain | Residue |
| A | PRO209 |
| A | LEU210 |
| A | GLN211 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 324 |
| Chain | Residue |
| A | GLN40 |
| A | GLN44 |
| A | ASN159 |
| A | GLY176 |
| A | ASN194 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 313 |
| Chain | Residue |
| B | ARG151 |
| B | ASN168 |
| B | SER187 |
| B | HOH362 |
| B | HOH365 |
| site_id | BC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 B 314 |
| Chain | Residue |
| B | ASP180 |
| B | THR181 |
| B | GLY199 |
| B | HOH323 |
| B | HOH345 |
| B | HOH347 |
| B | HOH376 |
| B | HOH511 |
| B | HOH961 |
| C | THR184 |
| C | HOH322 |
| C | HOH349 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 315 |
| Chain | Residue |
| B | GLN43 |
| B | VAL93 |
| B | HIS94 |
| B | GLN95 |
| B | TRP96 |
| B | HOH367 |
| B | HOH396 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 316 |
| Chain | Residue |
| A | LYS280 |
| B | THR133 |
| B | ALA134 |
| B | HOH422 |
| B | HOH893 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 317 |
| Chain | Residue |
| B | SER62 |
| B | ALA63 |
| B | HOH497 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 C 313 |
| Chain | Residue |
| A | THR184 |
| A | HOH338 |
| A | HOH917 |
| C | ASP180 |
| C | THR181 |
| C | GLY199 |
| C | HOH325 |
| C | HOH364 |
| C | HOH391 |
| C | HOH907 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 314 |
| Chain | Residue |
| C | TRP96 |
| C | HOH918 |
| C | HOH919 |
| C | GLN43 |
| C | VAL93 |
| C | HIS94 |
| C | GLN95 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 315 |
| Chain | Residue |
| B | LYS280 |
| C | THR133 |
| C | ALA134 |
| C | HOH518 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 316 |
| Chain | Residue |
| C | TRP50 |
| C | ARG53 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 317 |
| Chain | Residue |
| A | TYR287 |
| C | SER242 |
| C | MET243 |
| C | VAL273 |
| C | ALA274 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. VDegTmVdtwAtVGscAqIGknVhLsggV |
| Chain | Residue | Details |
| A | VAL173-VAL201 |
