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3TIA

Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir

Functional Information from GO Data
ChainGOidnamespacecontents
A0004308molecular_functionexo-alpha-sialidase activity
A0005975biological_processcarbohydrate metabolic process
A0016020cellular_componentmembrane
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0020002cellular_componenthost cell plasma membrane
A0033644cellular_componenthost cell membrane
A0044423cellular_componentvirion component
A0046761biological_processviral budding from plasma membrane
A0046872molecular_functionmetal ion binding
A0052794molecular_functionexo-alpha-(2->3)-sialidase activity
A0052795molecular_functionexo-alpha-(2->6)-sialidase activity
A0052796molecular_functionexo-alpha-(2->8)-sialidase activity
A0055036cellular_componentvirion membrane
B0004308molecular_functionexo-alpha-sialidase activity
B0005975biological_processcarbohydrate metabolic process
B0016020cellular_componentmembrane
B0016798molecular_functionhydrolase activity, acting on glycosyl bonds
B0020002cellular_componenthost cell plasma membrane
B0033644cellular_componenthost cell membrane
B0044423cellular_componentvirion component
B0046761biological_processviral budding from plasma membrane
B0046872molecular_functionmetal ion binding
B0052794molecular_functionexo-alpha-(2->3)-sialidase activity
B0052795molecular_functionexo-alpha-(2->6)-sialidase activity
B0052796molecular_functionexo-alpha-(2->8)-sialidase activity
B0055036cellular_componentvirion membrane
C0004308molecular_functionexo-alpha-sialidase activity
C0005975biological_processcarbohydrate metabolic process
C0016020cellular_componentmembrane
C0016798molecular_functionhydrolase activity, acting on glycosyl bonds
C0020002cellular_componenthost cell plasma membrane
C0033644cellular_componenthost cell membrane
C0044423cellular_componentvirion component
C0046761biological_processviral budding from plasma membrane
C0046872molecular_functionmetal ion binding
C0052794molecular_functionexo-alpha-(2->3)-sialidase activity
C0052795molecular_functionexo-alpha-(2->6)-sialidase activity
C0052796molecular_functionexo-alpha-(2->8)-sialidase activity
C0055036cellular_componentvirion membrane
D0004308molecular_functionexo-alpha-sialidase activity
D0005975biological_processcarbohydrate metabolic process
D0016020cellular_componentmembrane
D0016798molecular_functionhydrolase activity, acting on glycosyl bonds
D0020002cellular_componenthost cell plasma membrane
D0033644cellular_componenthost cell membrane
D0044423cellular_componentvirion component
D0046761biological_processviral budding from plasma membrane
D0046872molecular_functionmetal ion binding
D0052794molecular_functionexo-alpha-(2->3)-sialidase activity
D0052795molecular_functionexo-alpha-(2->6)-sialidase activity
D0052796molecular_functionexo-alpha-(2->8)-sialidase activity
D0055036cellular_componentvirion membrane
Functional Information from PROSITE/UniProt
site_idPS00022
Number of Residues12
DetailsEGF_1 EGF-like domain signature 1. CsCypRypGVrC
ChainResidueDetails
ACYS278-CYS289

219140

PDB entries from 2024-05-01

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