Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0008927 | molecular_function | mannonate dehydratase activity |
| A | 0009063 | biological_process | amino acid catabolic process |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0008927 | molecular_function | mannonate dehydratase activity |
| B | 0009063 | biological_process | amino acid catabolic process |
| B | 0016052 | biological_process | carbohydrate catabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0008927 | molecular_function | mannonate dehydratase activity |
| C | 0009063 | biological_process | amino acid catabolic process |
| C | 0016052 | biological_process | carbohydrate catabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 500 |
| Chain | Residue |
| A | ASP211 |
| A | GLU237 |
| A | GLU263 |
| A | HOH459 |
| A | HOH527 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 404 |
| Chain | Residue |
| A | PRO81 |
| A | PRO81 |
| A | VAL82 |
| A | VAL82 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | GLU220 |
| A | ARG232 |
| A | PRO233 |
| A | PRO258 |
| A | HOH412 |
| A | HOH442 |
| A | HOH529 |
| A | HOH553 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL A 406 |
| Chain | Residue |
| A | ASN38 |
| A | TYR76 |
| A | TRP77 |
| A | TYR160 |
| A | HIS213 |
| A | GLU263 |
| A | HIS313 |
| A | ALA315 |
| A | ASP317 |
| A | TRP403 |
| A | HOH527 |
| A | HOH643 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 500 |
| Chain | Residue |
| B | ASP211 |
| B | GLU237 |
| B | GLU263 |
| B | HOH440 |
| B | HOH597 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 404 |
| Chain | Residue |
| B | PRO81 |
| B | VAL82 |
| C | PRO81 |
| C | VAL82 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL B 405 |
| Chain | Residue |
| B | ASN38 |
| B | TYR160 |
| B | HIS213 |
| B | GLU263 |
| B | HIS313 |
| B | ALA315 |
| B | ASP317 |
| B | HOH552 |
| B | HOH597 |
| C | TYR76 |
| C | TRP77 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 406 |
| Chain | Residue |
| B | TYR107 |
| B | ALA113 |
| B | ARG115 |
| B | GLU116 |
| B | LEU331 |
| B | HIS364 |
| B | HOH796 |
| C | ARG63 |
| C | HOH582 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 407 |
| Chain | Residue |
| B | GLU220 |
| B | ARG232 |
| B | PRO233 |
| B | PRO258 |
| B | HOH423 |
| B | HOH439 |
| B | HOH517 |
| B | HOH530 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 500 |
| Chain | Residue |
| C | ASP211 |
| C | GLU237 |
| C | GLU263 |
| C | HOH447 |
| C | HOH547 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL C 404 |
| Chain | Residue |
| B | TYR76 |
| B | TRP77 |
| C | ASN38 |
| C | TYR160 |
| C | HIS213 |
| C | GLU263 |
| C | HIS313 |
| C | ALA315 |
| C | ASP317 |
| C | TRP403 |
| C | HOH547 |
| C | HOH604 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 405 |
| Chain | Residue |
| C | GLU220 |
| C | ARG232 |
| C | PRO233 |
| C | PRO258 |
| C | HOH441 |
| C | HOH488 |
| C | HOH877 |
| C | HOH878 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 406 |
| Chain | Residue |
| B | ARG63 |
| B | HOH607 |
| C | TYR107 |
| C | ALA113 |
| C | ARG115 |
| C | GLU116 |
| C | HIS364 |
| C | HOH800 |
Functional Information from PROSITE/UniProt
| site_id | PS00908 |
| Number of Residues | 26 |
| Details | MR_MLE_1 Mandelate racemase / muconate lactonizing enzyme family signature 1. AiAAVDmALwDIkGKiaglPVyqLLG |
| Chain | Residue | Details |
| A | ALA86-GLY111 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24697546","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Site: {"description":"Important for activity and substrate specificity; Ala is observed in family members with high D-mannonate dehydratase activity that have no activity with D-gluconate","evidences":[{"evidenceCode":"ECO:0000250"}]} |
