3THI
THIAMINASE I FROM BACILLUS THIAMINOLYTICUS
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 380 |
| Chain | Residue |
| A | HIS282 |
| A | HIS282 |
| A | PRO283 |
| A | PRO283 |
| A | GLU284 |
| A | LEU285 |
| site_id | NUC |
| Number of Residues | 1 |
| Details | CYS 113 IS THE ACTIVE SITE NUCLEOPHILE. |
| Chain | Residue |
| A | CYS113 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"8631946","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9843405","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"9843405","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2thi |
| Chain | Residue | Details |
| A | CYS113 | |
| A | GLU241 |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 357 |
| Chain | Residue | Details |
| A | CYS113 | activator, covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | GLU241 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASP272 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, steric role |
