Functional Information from GO Data
| Chain | GOid | namespace | contents |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA E 500 |
| Chain | Residue |
| E | GLU70 |
| E | ASN72 |
| E | VAL75 |
| E | GLU77 |
| E | GLU80 |
| E | HOH513 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 I 990 |
| Chain | Residue |
| I | PHE4 |
| I | ARG42 |
| I | HOH538 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 I 991 |
| Chain | Residue |
| E | GLN239 |
| I | ARG20 |
| I | TYR35 |
| I | HOH636 |
| I | HOH671 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 I 992 |
| Chain | Residue |
| E | LYS60 |
| I | ILE18 |
| I | ARG20 |
| I | LYS46 |
| site_id | CAT |
| Number of Residues | 3 |
| Details | THE CATALYTIC TRIAD |
| Chain | Residue |
| E | HIS57 |
| E | ASP102 |
| E | SER195 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| E | VAL53-CYS58 | |
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FvyGGCrakrnnFksaedC |
| Chain | Residue | Details |
| I | PHE33-CYS51 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for specificity","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 50 |
| Details | Domain: {"description":"BPTI/Kunitz inhibitor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00031","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Reactive bond for trypsin"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | SER195 | |
| E | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | SER195 | |
| E | HIS57 | |
| E | GLY196 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | SER195 | |
| E | GLY193 | |
| E | HIS57 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY193 | |
| E | ASP95 | |
| E | HIS57 | |
