Functional Information from GO Data
| Chain | GOid | namespace | contents |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA E 800 |
| Chain | Residue |
| E | GLU70 |
| E | ASN72 |
| E | VAL75 |
| E | GLU77 |
| E | GLU80 |
| E | HOH555 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 I 990 |
| Chain | Residue |
| I | PHE4 |
| I | LYS41 |
| I | ARG42 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 I 991 |
| site_id | CAT |
| Number of Residues | 3 |
| Details | THE CATALYTIC TRIAD. |
| Chain | Residue |
| E | HIS57 |
| E | ASP102 |
| E | ALA195 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| E | VAL53-CYS58 | |
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FvyGGCrakrnnFksaedC |
| Chain | Residue | Details |
| I | PHE33-CYS51 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Reactive bond for trypsin |
| Chain | Residue | Details |
| I | LYS15 | |
| E | ASP102 | |
| E | ALA195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| E | GLU70 | |
| E | ASN72 | |
| E | VAL75 | |
| E | GLU80 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| E | ASP189 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ALA195 | |
| E | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ALA195 | |
| E | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | ALA195 | |
| E | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | ALA195 | |
| E | GLY193 | |
| E | HIS57 | |
| site_id | CSA6 |
| Number of Residues | 7 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | GLN192 | |
| E | ASP102 | |
| E | ALA195 | |
| E | GLY193 | |
| E | CYS191 | |
| E | HIS57 | |
| E | ASP194 | |
