3TGB
Crystal structure of L130R mutant of Nitrophorin 4 from Rhodnius prolixus complexed with imidazole at pH 7.4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042311 | biological_process | vasodilation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051381 | molecular_function | histamine binding |
| A | 0070026 | molecular_function | nitric oxide binding |
| A | 0097746 | biological_process | blood vessel diameter maintenance |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM A 185 |
| Chain | Residue |
| A | TYR28 |
| A | LYS88 |
| A | TYR105 |
| A | PHE107 |
| A | LEU123 |
| A | LYS125 |
| A | ARG130 |
| A | LEU133 |
| A | IMD186 |
| A | HOH290 |
| A | HOH389 |
| A | VAL36 |
| A | PRO37 |
| A | TYR40 |
| A | GLU55 |
| A | LEU57 |
| A | HIS59 |
| A | ASP70 |
| A | PHE86 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD A 186 |
| Chain | Residue |
| A | LEU123 |
| A | LEU133 |
| A | HEM185 |
| A | HOH250 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: proximal binding residue => ECO:0000269|PubMed:10876239, ECO:0000269|PubMed:11560480, ECO:0000269|PubMed:14673714, ECO:0000269|PubMed:16171383, ECO:0000269|PubMed:20524697, ECO:0000269|PubMed:22334402, ECO:0000269|PubMed:22976968, ECO:0000269|PubMed:23474537, ECO:0000269|PubMed:9782054 |
| Chain | Residue | Details |
| A | HIS59 |
