3TFC
1.95 Angstrom crystal structure of a bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase (aroA) from Listeria monocytogenes EGD-e in complex with phosphoenolpyruvate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004106 | molecular_function | chorismate mutase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0046417 | biological_process | chorismate metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004106 | molecular_function | chorismate mutase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0046417 | biological_process | chorismate metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 362 |
| Chain | Residue |
| A | CYS126 |
| A | HIS296 |
| A | GLU322 |
| A | ASP333 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEP A 1268 |
| Chain | Residue |
| A | ALA209 |
| A | ARG210 |
| A | LYS231 |
| A | ARG261 |
| A | HIS296 |
| A | HOH365 |
| A | ARG150 |
| A | LYS155 |
| A | GLU188 |
| A | GLN206 |
| A | GLY208 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 363 |
| Chain | Residue |
| A | ARG157 |
| A | THR158 |
| A | HOH512 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 362 |
| Chain | Residue |
| B | CYS126 |
| B | HIS296 |
| B | GLU322 |
| B | ASP333 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PEP B 1269 |
| Chain | Residue |
| B | ARG150 |
| B | LYS155 |
| B | GLU188 |
| B | GLN206 |
| B | GLY208 |
| B | ALA209 |
| B | ARG210 |
| B | LYS231 |
| B | ARG261 |
| B | HIS296 |
| B | HOH386 |
| B | HOH409 |
| B | HOH473 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 363 |
| Chain | Residue |
| B | ARG157 |
| B | THR158 |
