3TCX

Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005178	molecular_function	integrin binding
A	0007155	biological_process	cell adhesion
C	0005178	molecular_function	integrin binding
C	0007155	biological_process	cell adhesion
E	0005178	molecular_function	integrin binding
E	0007155	biological_process	cell adhesion
G	0005178	molecular_function	integrin binding
G	0007155	biological_process	cell adhesion
I	0005178	molecular_function	integrin binding
I	0007155	biological_process	cell adhesion
K	0005178	molecular_function	integrin binding
K	0007155	biological_process	cell adhesion
M	0005178	molecular_function	integrin binding
M	0007155	biological_process	cell adhesion
O	0005178	molecular_function	integrin binding
O	0007155	biological_process	cell adhesion
Q	0005178	molecular_function	integrin binding
Q	0007155	biological_process	cell adhesion
S	0005178	molecular_function	integrin binding
S	0007155	biological_process	cell adhesion
U	0005178	molecular_function	integrin binding
U	0007155	biological_process	cell adhesion
W	0005178	molecular_function	integrin binding
W	0007155	biological_process	cell adhesion
Y	0005178	molecular_function	integrin binding
Y	0007155	biological_process	cell adhesion
a	0005178	molecular_function	integrin binding
a	0007155	biological_process	cell adhesion

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 901

Chain	Residue
A	GLU34
B	SER139
B	SER141
B	THR206
B	ASP239
B	GLU241

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 901

Chain	Residue
D	THR206
D	ASP239
D	GLU241
C	GLU34
D	SER139
D	SER141

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG F 901

Chain	Residue
E	GLU34
F	ASP137
F	SER139
F	SER141
F	THR206
F	ASP239
F	GLU241

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG H 901

Chain	Residue
G	GLU34
H	SER139
H	SER141
H	THR206
H	ASP239
H	GLU241

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG J 901

Chain	Residue
I	GLU34
J	SER139
J	SER141
J	THR206
J	ASP239
J	GLU241

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG L 901

Chain	Residue
K	GLU34
L	SER139
L	SER141
L	THR206
L	ASP239
L	GLU241

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG N 901

Chain	Residue
M	GLU34
N	SER139
N	SER141
N	THR206
N	ASP239
N	GLU241

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG P 901

Chain	Residue
O	GLU34
P	SER139
P	SER141
P	THR206
P	ASP239
P	GLU241

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG R 901

Chain	Residue
Q	GLU34
R	ASP137
R	SER139
R	SER141
R	THR206
R	ASP239
R	GLU241

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG T 901

Chain	Residue
S	GLU34
T	ASP137
T	SER139
T	SER141
T	THR206
T	ASP239
T	GLU241

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG V 901

Chain	Residue
U	GLU34
V	ASP137
V	SER139
V	SER141
V	THR206
V	ASP239
V	GLU241

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG X 901

Chain	Residue
W	GLU34
X	SER139
X	SER141
X	THR206
X	ASP239
X	GLU241

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG Z 901

Chain	Residue
Y	GLU34
Z	SER139
Z	SER141
Z	THR206
Z	ASP239
Z	GLU241

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG b 901

Chain	Residue
a	GLU34
b	ASP137
b	SER139
b	SER141
b	THR206
b	ASP239
b	GLU241

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	868
Details	Domain: {"description":"Ig-like C2-type 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2394
Details	Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	14
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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