3TB3

Crystal structure of the UCH domain of UCH-L5 with 6 residues deleted

Replaces:  3SQA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004843	molecular_function	cysteine-type deubiquitinase activity
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0016579	biological_process	protein deubiquitination
A	0031011	cellular_component	Ino80 complex
A	0070628	molecular_function	proteasome binding
B	0004843	molecular_function	cysteine-type deubiquitinase activity
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0016579	biological_process	protein deubiquitination
B	0031011	cellular_component	Ino80 complex
B	0070628	molecular_function	proteasome binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 228

Chain	Residue
A	GLU109
A	GLU113
B	GLU113
B	HOH247
B	HOH248

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA B 229

Chain	Residue
B	GLU109
B	GLU113

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01393","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01393","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PROSITE-ProRule","id":"PRU01393","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Important for enzyme activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01393","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9WUP7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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