3TB2
1-Cys peroxidoxin from Plasmodium Yoelli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0016209 | molecular_function | antioxidant activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0051920 | molecular_function | peroxiredoxin activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0016209 | molecular_function | antioxidant activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0051920 | molecular_function | peroxiredoxin activity |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0004601 | molecular_function | peroxidase activity |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005829 | cellular_component | cytosol |
| C | 0016209 | molecular_function | antioxidant activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0034599 | biological_process | cellular response to oxidative stress |
| C | 0045454 | biological_process | cell redox homeostasis |
| C | 0051920 | molecular_function | peroxiredoxin activity |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0004601 | molecular_function | peroxidase activity |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005829 | cellular_component | cytosol |
| D | 0016209 | molecular_function | antioxidant activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0034599 | biological_process | cellular response to oxidative stress |
| D | 0045454 | biological_process | cell redox homeostasis |
| D | 0051920 | molecular_function | peroxiredoxin activity |
| D | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 221 |
| Chain | Residue |
| A | LEU92 |
| A | ASN93 |
| A | LYS94 |
| A | HOH268 |
| A | HOH506 |
| C | LYS94 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 222 |
| Chain | Residue |
| A | LYS212 |
| A | LYS213 |
| D | LYS15 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 223 |
| Chain | Residue |
| A | PRO40 |
| A | PRO45 |
| A | VAL46 |
| A | CSD47 |
| A | GLU118 |
| A | ARG129 |
| A | ALA148 |
| A | HOH558 |
| C | ALA173 |
| C | ILE187 |
| C | PRO188 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 224 |
| Chain | Residue |
| A | ASN153 |
| A | HIS155 |
| C | ASN177 |
| C | ASN179 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 225 |
| Chain | Residue |
| A | LEU111 |
| A | THR143 |
| C | HIS4 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 226 |
| Chain | Residue |
| A | ASN11 |
| A | PHE12 |
| A | THR13 |
| A | HOH562 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 227 |
| Chain | Residue |
| A | ILE121 |
| A | GLY123 |
| B | SER104 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 228 |
| Chain | Residue |
| A | GLU207 |
| A | PRO209 |
| C | TYR88 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 229 |
| Chain | Residue |
| A | TYR89 |
| A | LYS91 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 221 |
| Chain | Residue |
| B | LYS212 |
| B | LYS213 |
| C | LYS15 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL B 222 |
| Chain | Residue |
| B | PRO40 |
| B | THR44 |
| B | PRO45 |
| B | VAL46 |
| B | CSD47 |
| B | ARG129 |
| B | ALA148 |
| B | HOH554 |
| D | ALA173 |
| D | ILE187 |
| D | PRO188 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 223 |
| Chain | Residue |
| B | GLU207 |
| B | MET208 |
| B | PRO209 |
| D | TYR88 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 224 |
| Chain | Residue |
| B | ASN153 |
| B | HIS155 |
| B | GLU156 |
| B | HOH651 |
| D | ASN153 |
| D | EDO226 |
| D | EDO227 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 225 |
| Chain | Residue |
| B | TYR168 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 221 |
| Chain | Residue |
| C | LYS212 |
| C | LYS213 |
| C | HOH437 |
| site_id | BC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL C 222 |
| Chain | Residue |
| A | ALA173 |
| A | PRO188 |
| C | THR44 |
| C | PRO45 |
| C | VAL46 |
| C | CSD47 |
| C | ARG129 |
| C | ALA148 |
| C | HOH555 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 223 |
| Chain | Residue |
| A | TYR146 |
| A | GLU156 |
| C | LEU131 |
| C | TYR146 |
| C | ARG152 |
| C | ASN153 |
| C | GLU156 |
| C | HOH231 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 224 |
| Chain | Residue |
| A | ASN177 |
| A | ASN179 |
| C | ASN153 |
| C | HIS155 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 225 |
| Chain | Residue |
| A | TYR88 |
| C | GLU207 |
| C | MET208 |
| C | PRO209 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 226 |
| Chain | Residue |
| C | THR167 |
| C | TYR168 |
| C | THR169 |
| C | THR170 |
| C | PRO171 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 227 |
| Chain | Residue |
| C | GLU24 |
| C | TYR28 |
| C | PHE23 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 228 |
| Chain | Residue |
| C | ASP182 |
| C | LYS183 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 221 |
| Chain | Residue |
| D | LYS212 |
| D | LYS213 |
| site_id | CC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL D 222 |
| Chain | Residue |
| B | ALA173 |
| B | ILE187 |
| B | PRO188 |
| D | PRO40 |
| D | THR44 |
| D | PRO45 |
| D | VAL46 |
| D | CSD47 |
| D | GLU118 |
| D | ARG129 |
| D | ALA148 |
| D | HOH553 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 223 |
| Chain | Residue |
| B | TYR88 |
| D | GLU207 |
| D | MET208 |
| D | PRO209 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 224 |
| Chain | Residue |
| D | THR122 |
| D | EDO225 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 225 |
| Chain | Residue |
| C | SER104 |
| D | GLY123 |
| D | EDO224 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 226 |
| Chain | Residue |
| B | ASN177 |
| B | ASN179 |
| B | EDO224 |
| D | ASN153 |
| D | HIS155 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 227 |
| Chain | Residue |
| B | ASN153 |
| B | HIS155 |
| B | EDO224 |
| D | ARG159 |
| D | ASN177 |
| D | ASN179 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 228 |
| Chain | Residue |
| D | THR167 |
| D | THR169 |
| D | THR170 |
| D | PRO171 |
