Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3TB2

1-Cys peroxidoxin from Plasmodium Yoelli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0045454	biological_process	cell redox homeostasis
A	0051920	molecular_function	peroxiredoxin activity
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0045454	biological_process	cell redox homeostasis
B	0051920	molecular_function	peroxiredoxin activity
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0045454	biological_process	cell redox homeostasis
C	0051920	molecular_function	peroxiredoxin activity
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0045454	biological_process	cell redox homeostasis
D	0051920	molecular_function	peroxiredoxin activity
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 221

Chain	Residue
A	LEU92
A	ASN93
A	LYS94
A	HOH268
A	HOH506
C	LYS94

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 222

Chain	Residue
A	LYS212
A	LYS213
D	LYS15

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 223

Chain	Residue
A	PRO40
A	PRO45
A	VAL46
A	CSD47
A	GLU118
A	ARG129
A	ALA148
A	HOH558
C	ALA173
C	ILE187
C	PRO188

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 224

Chain	Residue
A	ASN153
A	HIS155
C	ASN177
C	ASN179

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 225

Chain	Residue
A	LEU111
A	THR143
C	HIS4

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 226

Chain	Residue
A	ASN11
A	PHE12
A	THR13
A	HOH562

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 227

Chain	Residue
A	ILE121
A	GLY123
B	SER104

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 228

Chain	Residue
A	GLU207
A	PRO209
C	TYR88

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 229

Chain	Residue
A	TYR89
A	LYS91

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 221

Chain	Residue
B	LYS212
B	LYS213
C	LYS15

site_id	BC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL B 222

Chain	Residue
B	PRO40
B	THR44
B	PRO45
B	VAL46
B	CSD47
B	ARG129
B	ALA148
B	HOH554
D	ALA173
D	ILE187
D	PRO188

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 223

Chain	Residue
B	GLU207
B	MET208
B	PRO209
D	TYR88

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 224

Chain	Residue
B	ASN153
B	HIS155
B	GLU156
B	HOH651
D	ASN153
D	EDO226
D	EDO227

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO B 225

Chain	Residue
B	TYR168

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 221

Chain	Residue
C	LYS212
C	LYS213
C	HOH437

site_id	BC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL C 222

Chain	Residue
A	ALA173
A	PRO188
C	THR44
C	PRO45
C	VAL46
C	CSD47
C	ARG129
C	ALA148
C	HOH555

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO C 223

Chain	Residue
A	TYR146
A	GLU156
C	LEU131
C	TYR146
C	ARG152
C	ASN153
C	GLU156
C	HOH231

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 224

Chain	Residue
A	ASN177
A	ASN179
C	ASN153
C	HIS155

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 225

Chain	Residue
A	TYR88
C	GLU207
C	MET208
C	PRO209

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO C 226

Chain	Residue
C	THR167
C	TYR168
C	THR169
C	THR170
C	PRO171

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO C 227

Chain	Residue
C	GLU24
C	TYR28
C	PHE23

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO C 228

Chain	Residue
C	ASP182
C	LYS183

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 221

Chain	Residue
D	LYS212
D	LYS213

site_id	CC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GOL D 222

Chain	Residue
B	ALA173
B	ILE187
B	PRO188
D	PRO40
D	THR44
D	PRO45
D	VAL46
D	CSD47
D	GLU118
D	ARG129
D	ALA148
D	HOH553

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO D 223

Chain	Residue
B	TYR88
D	GLU207
D	MET208
D	PRO209

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO D 224

Chain	Residue
D	THR122
D	EDO225

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO D 225

Chain	Residue
C	SER104
D	GLY123
D	EDO224

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 226

Chain	Residue
B	ASN177
B	ASN179
B	EDO224
D	ASN153
D	HIS155

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 227

Chain	Residue
B	ASN153
B	HIS155
B	EDO224
D	ARG159
D	ASN177
D	ASN179

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO D 228

Chain	Residue
D	THR167
D	THR169
D	THR170
D	PRO171

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)