3T7M
Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 263 |
| Chain | Residue |
| A | ASP102 |
| A | ASP104 |
| A | HIS212 |
| A | UDP264 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE UDP A 264 |
| Chain | Residue |
| A | ARG77 |
| A | LEU80 |
| A | THR83 |
| A | ASP102 |
| A | ALA103 |
| A | ASP104 |
| A | HIS212 |
| A | LEU214 |
| A | GLY215 |
| A | LYS218 |
| A | MN263 |
| A | HOH329 |
| A | HOH407 |
| A | HOH452 |
| A | LEU9 |
| A | THR10 |
| A | THR11 |
| A | ASN12 |
| A | TYR15 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 265 |
| Chain | Residue |
| A | SER142 |
| A | VAL143 |
| A | GLU144 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 266 |
| Chain | Residue |
| A | ILE179 |
| B | ASP178 |
| B | ILE179 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 267 |
| Chain | Residue |
| A | GLU119 |
| A | LEU120 |
| A | SER173 |
| A | TRP174 |
| A | LYS181 |
| A | HOH375 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 268 |
| Chain | Residue |
| A | ASN256 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 269 |
| Chain | Residue |
| A | HOH322 |
| A | HOH443 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 270 |
| Chain | Residue |
| A | PRO78 |
| A | GLU79 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 271 |
| Chain | Residue |
| A | HIS29 |
| A | ARG30 |
| A | ALA109 |
| A | ASN110 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 272 |
| Chain | Residue |
| A | ASP113 |
| A | ARG117 |
| A | TYR187 |
| A | HOH289 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 273 |
| Chain | Residue |
| A | ASP130 |
| A | CYS131 |
| A | ALA175 |
| A | HOH354 |
| B | PHE204 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 274 |
| Chain | Residue |
| A | GLY215 |
| A | ARG216 |
| A | HOH377 |
| A | HOH537 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 275 |
| Chain | Residue |
| A | PHE213 |
| A | TYR222 |
| A | ASN239 |
| A | HOH281 |
| A | HOH523 |
| A | HOH536 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 276 |
| Chain | Residue |
| A | ASP125 |
| A | GLY127 |
| A | GLN164 |
| A | LEU214 |
| A | HOH571 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 263 |
| Chain | Residue |
| B | ASP102 |
| B | ASP104 |
| B | HIS212 |
| B | UDP264 |
| site_id | BC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE UDP B 264 |
| Chain | Residue |
| B | LEU9 |
| B | THR10 |
| B | THR11 |
| B | ASN12 |
| B | TYR15 |
| B | ARG77 |
| B | LEU80 |
| B | THR83 |
| B | ASP102 |
| B | ALA103 |
| B | ASP104 |
| B | HIS212 |
| B | LEU214 |
| B | GLY215 |
| B | LYS218 |
| B | MN263 |
| B | HOH419 |
| B | HOH423 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 265 |
| Chain | Residue |
| B | GLU119 |
| B | LEU120 |
| B | SER173 |
| B | TRP174 |
| B | LYS181 |
| B | HOH345 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 266 |
| Chain | Residue |
| B | HOH431 |
| A | ARG34 |
| B | PRO41 |
| B | ARG48 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 267 |
| Chain | Residue |
| B | SER142 |
| B | VAL143 |
| B | GLU144 |
| B | HOH309 |
| B | HOH427 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 268 |
| Chain | Residue |
| A | PHE204 |
| B | ASP130 |
| B | ALA175 |
| B | HOH317 |
| B | HOH323 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 269 |
| Chain | Residue |
| B | ASP113 |
| B | LEU114 |
| B | ARG117 |
| B | TYR187 |
| B | HOH287 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 270 |
| Chain | Residue |
| B | GLN94 |
| B | SER96 |
| B | HOH448 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 271 |
| Chain | Residue |
| B | HIS29 |
| B | ASN110 |
| B | HOH387 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 272 |
| Chain | Residue |
| B | GLY215 |
| B | ARG216 |
| B | HOH467 |
| site_id | CC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 273 |
| Chain | Residue |
| A | ASP56 |
| A | GLU57 |
| A | HOH491 |
| B | PRO41 |
| B | VAL43 |
| B | SER44 |
| B | ASP45 |
| B | ARG48 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 274 |
| Chain | Residue |
| B | SER0 |
| B | ARG33 |
| B | HOH331 |
| B | HOH447 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 275 |
| Chain | Residue |
| A | SER196 |
| A | HOH570 |
| B | ASP125 |
| B | GLY127 |
| B | GLN164 |
| B | HOH414 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22160680","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3RMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3T7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P13280","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22160680","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3T7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3RMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3T7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"UniProtKB","id":"P13280","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P13280","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"O-linked (Glc...) tyrosine","evidences":[{"source":"PubMed","id":"22160680","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30356213","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3U2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3U2V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
