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3T2V

Crystal structure of the complex of peptidoglycan recognition protein-short (CPGRP-S) with mycolic acid at 2.5 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0001818biological_processnegative regulation of cytokine production
A0005576cellular_componentextracellular region
A0008270molecular_functionzinc ion binding
A0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
A0009253biological_processpeptidoglycan catabolic process
A0016019molecular_functionpeptidoglycan immune receptor activity
A0016045biological_processdetection of bacterium
A0042742biological_processdefense response to bacterium
A0042834molecular_functionpeptidoglycan binding
A0045087biological_processinnate immune response
A0050830biological_processdefense response to Gram-positive bacterium
B0001818biological_processnegative regulation of cytokine production
B0005576cellular_componentextracellular region
B0008270molecular_functionzinc ion binding
B0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
B0009253biological_processpeptidoglycan catabolic process
B0016019molecular_functionpeptidoglycan immune receptor activity
B0016045biological_processdetection of bacterium
B0042742biological_processdefense response to bacterium
B0042834molecular_functionpeptidoglycan binding
B0045087biological_processinnate immune response
B0050830biological_processdefense response to Gram-positive bacterium
C0001818biological_processnegative regulation of cytokine production
C0005576cellular_componentextracellular region
C0008270molecular_functionzinc ion binding
C0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
C0009253biological_processpeptidoglycan catabolic process
C0016019molecular_functionpeptidoglycan immune receptor activity
C0016045biological_processdetection of bacterium
C0042742biological_processdefense response to bacterium
C0042834molecular_functionpeptidoglycan binding
C0045087biological_processinnate immune response
C0050830biological_processdefense response to Gram-positive bacterium
D0001818biological_processnegative regulation of cytokine production
D0005576cellular_componentextracellular region
D0008270molecular_functionzinc ion binding
D0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
D0009253biological_processpeptidoglycan catabolic process
D0016019molecular_functionpeptidoglycan immune receptor activity
D0016045biological_processdetection of bacterium
D0042742biological_processdefense response to bacterium
D0042834molecular_functionpeptidoglycan binding
D0045087biological_processinnate immune response
D0050830biological_processdefense response to Gram-positive bacterium
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE TLA C 172
ChainResidue
CHIS37
DLEU153
DSER154
CALA39
CTHR152
CLEU153
CSER154
CGOL173
DHIS37
DALA39
DTHR152

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL C 173
ChainResidue
CPRO151
CTHR152
CTLA172
DHIS37
DALA39
DTYR71
DHIS146

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE KKJ D 172
ChainResidue
BASP2
BCYS6
BLEU134
DARG31
DARG138
DHOH212

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PDB entries from 2024-10-30

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