3SZT

Quorum Sensing Control Repressor, QscR, Bound to N-3-oxo-dodecanoyl-L-Homoserine Lactone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0003677	molecular_function	DNA binding
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0009372	biological_process	quorum sensing
A	0032993	cellular_component	protein-DNA complex
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	1900377	biological_process	negative regulation of secondary metabolite biosynthetic process
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0003677	molecular_function	DNA binding
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0009372	biological_process	quorum sensing
B	0032993	cellular_component	protein-DNA complex
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	1900377	biological_process	negative regulation of secondary metabolite biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE OHN A 238

Chain	Residue
A	SER38
A	ALA105
A	ILE125
A	HOH246
A	GLY40
A	TYR58
A	TRP62
A	TYR66
A	ASP75
A	LEU82
A	TRP90
A	TRP102

---

site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE OHN B 239

Chain	Residue
B	SER38
B	GLY40
B	ALA41
B	TYR52
B	PHE54
B	TYR58
B	TRP62
B	TYR66
B	ASP75
B	ILE77
B	VAL78
B	GLY81
B	LEU82
B	TRP90
B	TRP102
B	ILE110
B	SER126
B	MET127
B	SER129

---

Functional Information from PROSITE/UniProt

site_id	PS00622
Number of Residues	28
Details	HTH_LUXR_1 LuxR-type HTH domain signature. GktYgeIGliLsIdqrTVkfHivNAmrK

Chain	Residue	Details
A	GLY190-LYS217

---