Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 399 |
| Chain | Residue |
| A | TYR122 |
| A | HOH698 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE C8E A 400 |
| Chain | Residue |
| A | ALA211 |
| A | LEU213 |
| A | VAL249 |
| A | TRP316 |
| A | C8E410 |
| A | C8E413 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE C8E A 401 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE C8E A 402 |
| Chain | Residue |
| A | LEU142 |
| A | VAL323 |
| A | TYR325 |
| A | C8E412 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE C8E A 403 |
| Chain | Residue |
| A | HIS199 |
| A | HIS260 |
| A | TYR307 |
| A | C8E409 |
| A | C8E411 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE C8E A 404 |
| Chain | Residue |
| A | GLY321 |
| A | ARG344 |
| A | VAL346 |
| A | C8E405 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE C8E A 405 |
| Chain | Residue |
| A | ASN17 |
| A | LEU364 |
| A | HIS366 |
| A | LEU382 |
| A | C8E404 |
| A | HOH709 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE C8E A 406 |
| Chain | Residue |
| A | LEU15 |
| A | ARG16 |
| A | ASN17 |
| A | GLN39 |
| A | VAL384 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE C8E A 407 |
| Chain | Residue |
| A | LEU63 |
| A | PHE64 |
| A | GLY93 |
| A | VAL95 |
| A | C8E408 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE C8E A 408 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE C8E A 409 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE C8E A 410 |
| Chain | Residue |
| A | LEU314 |
| A | TRP316 |
| A | C8E400 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE C8E A 411 |
| Chain | Residue |
| A | PHE135 |
| A | ASN180 |
| A | TYR181 |
| A | ALA182 |
| A | HIS199 |
| A | ARG207 |
| A | C8E403 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE C8E A 412 |
| Chain | Residue |
| A | PRO143 |
| A | TYR186 |
| A | ARG344 |
| A | C8E402 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE C8E A 413 |
| Chain | Residue |
| A | LEU266 |
| A | GLN267 |
| A | ARG301 |
| A | SER302 |
| A | TRP303 |
| A | HIS327 |
| A | SER329 |
| A | C8E400 |
| site_id | BC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE VNL A 414 |
| Chain | Residue |
| A | LYS44 |
| A | PHE45 |
| A | ASP59 |
| A | ALA60 |
| A | ILE61 |
| A | GLU112 |
| A | MET113 |
| A | LEU114 |
| A | HOH504 |
| A | HOH548 |
| A | HOH578 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE VNL A 415 |
| Chain | Residue |
| A | HIS327 |
| A | LYS340 |
| A | TRP342 |
| A | ARG370 |
| A | ARG371 |
| A | SER372 |
| A | HOH695 |
| A | HOH816 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 399 |
| Chain | Residue |
| B | ALA226 |
| B | LEU252 |
| B | SER254 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 400 |
| Chain | Residue |
| B | LYS268 |
| B | GLY271 |
| B | ASP299 |
| B | HOH530 |
| B | HOH596 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 401 |
| Chain | Residue |
| B | LEU252 |
| B | TYR263 |
| B | ARG306 |
| B | HOH728 |
| B | HOH790 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE C8E B 402 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE C8E B 403 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE C8E B 404 |
| Chain | Residue |
| B | PHE64 |
| B | LEU43 |
| B | GLY62 |
| B | LEU63 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE C8E B 406 |
| Chain | Residue |
| B | ASN17 |
| B | TYR19 |
| B | TRP37 |
| B | HOH703 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE C8E B 407 |
| Chain | Residue |
| B | ASP116 |
| B | TYR122 |
| B | ASP124 |
| B | ARG284 |
| B | HOH781 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE C8E B 408 |
| Chain | Residue |
| B | VAL323 |
| B | C8E409 |
| B | C8E410 |
| site_id | CC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE C8E B 409 |
| Chain | Residue |
| B | PRO143 |
| B | TYR186 |
| B | TYR325 |
| B | TRP342 |
| B | ARG344 |
| B | C8E408 |
| B | C8E411 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE C8E B 410 |
| Chain | Residue |
| B | ALA182 |
| B | ALA184 |
| B | HIS199 |
| B | HIS260 |
| B | TYR307 |
| B | VAL323 |
| B | C8E408 |
| site_id | DC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE C8E B 411 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE C8E B 412 |
| Chain | Residue |
| A | TRP37 |
| B | PHE41 |
| B | VAL66 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE C8E B 413 |
| Chain | Residue |
| B | ARG94 |
| B | ASP162 |
| B | MET163 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE C8E B 415 |
| Chain | Residue |
| B | HIS215 |
| B | GLY225 |
| B | PHE253 |
| B | SER254 |
| site_id | DC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE VNL B 417 |
| Chain | Residue |
| B | LYS44 |
| B | PHE45 |
| B | ASP59 |
| B | ALA60 |
| B | ILE61 |
| B | LYS109 |
| B | GLU112 |
| B | MET113 |
| B | LEU114 |
| B | HOH434 |
| B | HOH533 |
| B | HOH543 |
| B | HOH639 |
| site_id | DC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE VNL B 418 |
| Chain | Residue |
| A | HOH552 |
| B | HIS327 |
| B | LYS340 |
| B | GLU341 |
| B | TRP342 |
| B | ARG370 |
| B | ARG371 |
| B | SER372 |
| B | HOH561 |
| B | HOH600 |
| B | HOH630 |
