3SW5

Crystal structure of inorganic pyrophosphatase from Bartonella henselae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004427	molecular_function	inorganic diphosphate phosphatase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004427	molecular_function	inorganic diphosphate phosphatase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006796	biological_process	phosphate-containing compound metabolic process
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004427	molecular_function	inorganic diphosphate phosphatase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006796	biological_process	phosphate-containing compound metabolic process
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004427	molecular_function	inorganic diphosphate phosphatase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006796	biological_process	phosphate-containing compound metabolic process
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004427	molecular_function	inorganic diphosphate phosphatase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006796	biological_process	phosphate-containing compound metabolic process
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0004427	molecular_function	inorganic diphosphate phosphatase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006796	biological_process	phosphate-containing compound metabolic process
F	0016787	molecular_function	hydrolase activity
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE LMR A 201

Chain	Residue
A	ASN76
A	THR77
A	ARG78
A	THR115
A	ARG117
A	TYR118
A	HOH186
A	HOH215
C	PHE45

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LMR B 201

Chain	Residue
B	ASN76
B	THR77
B	ARG78
B	THR115
B	ARG117
B	TYR118
B	HOH206
B	HOH236
B	HOH295
D	PHE45

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LMR C 201

Chain	Residue
C	ASN76
C	THR77
C	ARG78
C	THR115
C	ARG117
C	TYR118
C	HOH181
C	HOH197
F	PHE45
F	HOH190

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LMR D 201

Chain	Residue
D	ASN76
D	THR77
D	ARG78
D	THR115
D	ARG117
D	TYR118
D	HOH183
D	HOH192
D	HOH233
E	PHE45

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LMR E 201

Chain	Residue
B	PHE45
B	HOH191
E	ASN76
E	THR77
E	ARG78
E	THR115
E	ARG117
E	TYR118
E	HOH183
E	HOH193

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LMR F 201

Chain	Residue
A	PHE45
A	HOH205
F	ASN76
F	THR77
F	ARG78
F	THR115
F	ARG117
F	TYR118
F	HOH179
F	HOH193

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Functional Information from PROSITE/UniProt

site_id	PS00387
Number of Residues	7
Details	PPASE Inorganic pyrophosphatase signature. DGDPIDV

Chain	Residue	Details
A	ASP66-VAL72

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