3SV7

Crystal structure of NS3/4A protease variant R155K in complex with Telaprevir

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0019087	biological_process	transformation of host cell by virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE SV6 A 1

Chain	Residue
A	HOH115
A	SER1139
A	LYS1155
A	ALA1156
A	ALA1157
A	SER1159
A	ASP1168
A	HOH153
A	HIS982
A	GLN1041
A	THR1042
A	HIS1057
A	LEU1135
A	GLY1137
A	SER1138

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 2

Chain	Residue
A	HOH22
A	HOH23
A	HOH66
A	TYR1006
A	GLN1008
A	TYR1056

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 3

Chain	Residue
A	HOH145
A	CYS1097
A	CYS1099
A	CYS1145
A	HIS1149

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