3STM
Structure of human LFABP in complex with one molecule of palmitic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0003682 | molecular_function | chromatin binding |
| X | 0005319 | molecular_function | lipid transporter activity |
| X | 0005324 | molecular_function | long-chain fatty acid transmembrane transporter activity |
| X | 0005504 | molecular_function | fatty acid binding |
| X | 0005515 | molecular_function | protein binding |
| X | 0005634 | cellular_component | nucleus |
| X | 0005654 | cellular_component | nucleoplasm |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0005782 | cellular_component | peroxisomal matrix |
| X | 0005829 | cellular_component | cytosol |
| X | 0006869 | biological_process | lipid transport |
| X | 0008289 | molecular_function | lipid binding |
| X | 0015485 | molecular_function | cholesterol binding |
| X | 0015908 | biological_process | fatty acid transport |
| X | 0015909 | biological_process | long-chain fatty acid transport |
| X | 0016209 | molecular_function | antioxidant activity |
| X | 0019216 | biological_process | regulation of lipid metabolic process |
| X | 0019433 | biological_process | triglyceride catabolic process |
| X | 0032934 | molecular_function | sterol binding |
| X | 0036042 | molecular_function | long-chain fatty acyl-CoA binding |
| X | 0042167 | biological_process | heme catabolic process |
| X | 0070062 | cellular_component | extracellular exosome |
| X | 0070301 | biological_process | cellular response to hydrogen peroxide |
| X | 0071456 | biological_process | cellular response to hypoxia |
| X | 0098869 | biological_process | cellular oxidant detoxification |
| X | 0120009 | biological_process | intermembrane lipid transfer |
| X | 0120013 | molecular_function | lipid transfer activity |
| X | 0140104 | molecular_function | molecular carrier activity |
| X | 1990748 | biological_process | cellular detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PLM X 130 |
| Chain | Residue |
| X | SER39 |
| X | PHE50 |
| X | GLU72 |
| X | THR102 |
| X | ASN111 |
| X | ARG122 |
| X | HOH132 |
Functional Information from PROSITE/UniProt
| site_id | PS00214 |
| Number of Residues | 18 |
| Details | FABP Cytosolic fatty-acid binding proteins signature. GKYqLqsQeNFEaFMKAI |
| Chain | Residue | Details |
| X | GLY5-ILE22 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P12710","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02692","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P12710","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
