3STF

Crystal structure of a mutant (S211A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
A	0009058	biological_process	biosynthetic process
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0016740	molecular_function	transferase activity
A	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
B	0009058	biological_process	biosynthetic process
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0016740	molecular_function	transferase activity
B	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
C	0009058	biological_process	biosynthetic process
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0016740	molecular_function	transferase activity
C	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008676	molecular_function	3-deoxy-8-phosphooctulonate synthase activity
D	0009058	biological_process	biosynthetic process
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0016740	molecular_function	transferase activity
D	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 281

Chain	Residue
B	LYS52
B	GLN110
B	LYS135
B	PHE234

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B 282

Chain	Residue
B	SER273
B	HOH554
B	HOH579
B	ASN23
B	VAL24
B	ARG60
B	SER61
B	TYR66

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 281

Chain	Residue
B	HOH351
C	ALA103
C	CYS106
C	ASN130
C	HOH572
C	HOH573

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