3SQ8
Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase 1 H432R Mutant (SCAN1 Mutant)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0006281 | biological_process | DNA repair |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006281 | biological_process | DNA repair |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006281 | biological_process | DNA repair |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006281 | biological_process | DNA repair |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:16751265 |
| Chain | Residue | Details |
| A | NEP182 | |
| B | NEP182 | |
| C | NEP182 | |
| D | NEP182 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:17707402 |
| Chain | Residue | Details |
| A | ARG432 | |
| B | ARG432 | |
| C | ARG432 | |
| D | ARG432 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9NUW8 |
| Chain | Residue | Details |
| A | LYS184 | |
| A | LYS434 | |
| B | LYS184 | |
| B | LYS434 | |
| C | LYS184 | |
| C | LYS434 | |
| D | LYS184 | |
| D | LYS434 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Interaction with DNA => ECO:0000250|UniProtKB:Q9NUW8 |
| Chain | Residue | Details |
| A | SER467 | |
| B | SER467 | |
| C | SER467 | |
| D | SER467 |
