Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3SIV

Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0000492	biological_process	box C/D snoRNP assembly
A	0001651	cellular_component	dense fibrillar component
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005690	cellular_component	U4atac snRNP
A	0005730	cellular_component	nucleolus
A	0006397	biological_process	mRNA processing
A	0007338	biological_process	single fertilization
A	0008380	biological_process	RNA splicing
A	0030490	biological_process	maturation of SSU-rRNA
A	0030515	molecular_function	snoRNA binding
A	0030621	molecular_function	U4 snRNA binding
A	0030622	molecular_function	U4atac snRNA binding
A	0031428	cellular_component	box C/D methylation guide snoRNP complex
A	0032040	cellular_component	small-subunit processome
A	0032991	cellular_component	protein-containing complex
A	0034511	molecular_function	U3 snoRNA binding
A	0034512	molecular_function	box C/D sno(s)RNA binding
A	0042254	biological_process	ribosome biogenesis
A	0042274	biological_process	ribosomal small subunit biogenesis
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0051117	molecular_function	ATPase binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071011	cellular_component	precatalytic spliceosome
A	1990904	cellular_component	ribonucleoprotein complex
B	0000244	biological_process	spliceosomal tri-snRNP complex assembly
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0000492	biological_process	box C/D snoRNP assembly
D	0001651	cellular_component	dense fibrillar component
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005690	cellular_component	U4atac snRNP
D	0005730	cellular_component	nucleolus
D	0006397	biological_process	mRNA processing
D	0007338	biological_process	single fertilization
D	0008380	biological_process	RNA splicing
D	0030490	biological_process	maturation of SSU-rRNA
D	0030515	molecular_function	snoRNA binding
D	0030621	molecular_function	U4 snRNA binding
D	0030622	molecular_function	U4atac snRNA binding
D	0031428	cellular_component	box C/D methylation guide snoRNP complex
D	0032040	cellular_component	small-subunit processome
D	0032991	cellular_component	protein-containing complex
D	0034511	molecular_function	U3 snoRNA binding
D	0034512	molecular_function	box C/D sno(s)RNA binding
D	0042254	biological_process	ribosome biogenesis
D	0042274	biological_process	ribosomal small subunit biogenesis
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0051117	molecular_function	ATPase binding
D	0071005	cellular_component	U2-type precatalytic spliceosome
D	0071011	cellular_component	precatalytic spliceosome
D	1990904	cellular_component	ribonucleoprotein complex
E	0000244	biological_process	spliceosomal tri-snRNP complex assembly
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0000492	biological_process	box C/D snoRNP assembly
G	0001651	cellular_component	dense fibrillar component
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0005690	cellular_component	U4atac snRNP
G	0005730	cellular_component	nucleolus
G	0006397	biological_process	mRNA processing
G	0007338	biological_process	single fertilization
G	0008380	biological_process	RNA splicing
G	0030490	biological_process	maturation of SSU-rRNA
G	0030515	molecular_function	snoRNA binding
G	0030621	molecular_function	U4 snRNA binding
G	0030622	molecular_function	U4atac snRNA binding
G	0031428	cellular_component	box C/D methylation guide snoRNP complex
G	0032040	cellular_component	small-subunit processome
G	0032991	cellular_component	protein-containing complex
G	0034511	molecular_function	U3 snoRNA binding
G	0034512	molecular_function	box C/D sno(s)RNA binding
G	0042254	biological_process	ribosome biogenesis
G	0042274	biological_process	ribosomal small subunit biogenesis
G	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
G	0051117	molecular_function	ATPase binding
G	0071005	cellular_component	U2-type precatalytic spliceosome
G	0071011	cellular_component	precatalytic spliceosome
G	1990904	cellular_component	ribonucleoprotein complex
H	0000244	biological_process	spliceosomal tri-snRNP complex assembly
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0000492	biological_process	box C/D snoRNP assembly
J	0001651	cellular_component	dense fibrillar component
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0005690	cellular_component	U4atac snRNP
J	0005730	cellular_component	nucleolus
J	0006397	biological_process	mRNA processing
J	0007338	biological_process	single fertilization
J	0008380	biological_process	RNA splicing
J	0030490	biological_process	maturation of SSU-rRNA
J	0030515	molecular_function	snoRNA binding
J	0030621	molecular_function	U4 snRNA binding
J	0030622	molecular_function	U4atac snRNA binding
J	0031428	cellular_component	box C/D methylation guide snoRNP complex
J	0032040	cellular_component	small-subunit processome
J	0032991	cellular_component	protein-containing complex
J	0034511	molecular_function	U3 snoRNA binding
J	0034512	molecular_function	box C/D sno(s)RNA binding
J	0042254	biological_process	ribosome biogenesis
J	0042274	biological_process	ribosomal small subunit biogenesis
J	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0051117	molecular_function	ATPase binding
J	0071005	cellular_component	U2-type precatalytic spliceosome
J	0071011	cellular_component	precatalytic spliceosome
J	1990904	cellular_component	ribonucleoprotein complex
K	0000244	biological_process	spliceosomal tri-snRNP complex assembly
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex

Functional Information from PROSITE/UniProt

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CedknVPYvfVrSKqaLG

Chain	Residue	Details
A	CYS73-GLY90

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Interaction with U4 snRNA => ECO:0000269\|PubMed:17412961

Chain	Residue	Details
B	CYS247
E	CYS247
H	CYS247
K	CYS247
G	GLU61
G	LYS86
J	GLU61
J	LYS86

site_id	SWS_FT_FI2
Number of Residues	12
Details	SITE: Interaction with U4 snRNA and U4atac snRNA => ECO:0000269\|PubMed:17412961

Chain	Residue	Details
B	HIS270
K	HIS270
K	ARG293
K	LYS298
B	ARG293
B	LYS298
E	HIS270
E	ARG293
E	LYS298
H	HIS270
H	ARG293
H	LYS298

site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Interaction with U4atac snRNA => ECO:0000269\|PubMed:17412961

Chain	Residue	Details
B	ARG289
E	ARG289
H	ARG289
K	ARG289

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:Q9D0T1

Chain	Residue	Details
A	LYS21
D	LYS21
G	LYS21
J	LYS21

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
A	SER122
D	SER122
G	SER122
J	SER122

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)