3SE4
human IFNw-IFNAR ternary complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0002250 | biological_process | adaptive immune response |
| B | 0002286 | biological_process | T cell activation involved in immune response |
| B | 0002312 | biological_process | B cell activation involved in immune response |
| B | 0002323 | biological_process | natural killer cell activation involved in immune response |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0005126 | molecular_function | cytokine receptor binding |
| B | 0005132 | molecular_function | type I interferon receptor binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006952 | biological_process | defense response |
| B | 0006959 | biological_process | humoral immune response |
| B | 0009615 | biological_process | response to virus |
| B | 0043235 | cellular_component | receptor complex |
| B | 0043330 | biological_process | response to exogenous dsRNA |
| B | 0051607 | biological_process | defense response to virus |
| B | 0051726 | biological_process | regulation of cell cycle |
| B | 0060337 | biological_process | type I interferon-mediated signaling pathway |
| B | 0098586 | biological_process | cellular response to virus |
Functional Information from PROSITE/UniProt
| site_id | PS00252 |
| Number of Residues | 19 |
| Details | INTERFERON_A_B_D Interferon alpha, beta and delta family signature. YFqGIrvYLkekkysdCAW |
| Chain | Residue | Details |
| B | TYR125-TRP143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 100 |
| Details | Domain: {"description":"Fibronectin type-III 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21854986","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3S98","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000050","evidences":[{"source":"PubMed","id":"1693148","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"8181059","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
