3SE4
human IFNw-IFNAR ternary complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0002250 | biological_process | adaptive immune response |
| B | 0002286 | biological_process | T cell activation involved in immune response |
| B | 0002312 | biological_process | B cell activation involved in immune response |
| B | 0002323 | biological_process | natural killer cell activation involved in immune response |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0005126 | molecular_function | cytokine receptor binding |
| B | 0005132 | molecular_function | type I interferon receptor binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006952 | biological_process | defense response |
| B | 0006959 | biological_process | humoral immune response |
| B | 0009615 | biological_process | response to virus |
| B | 0043330 | biological_process | response to exogenous dsRNA |
| B | 0051607 | biological_process | defense response to virus |
| B | 0051726 | biological_process | regulation of cell cycle |
| B | 0060337 | biological_process | type I interferon-mediated signaling pathway |
| B | 0098586 | biological_process | cellular response to virus |
Functional Information from PROSITE/UniProt
| site_id | PS00252 |
| Number of Residues | 19 |
| Details | INTERFERON_A_B_D Interferon alpha, beta and delta family signature. YFqGIrvYLkekkysdCAW |
| Chain | Residue | Details |
| B | TYR125-TRP143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| C | ASN31 | |
| C | ASN89 | |
| C | ASN161 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8181059 |
| Chain | Residue | Details |
| C | ASN60 | |
| C | ASN165 | |
| A | ASN61 | |
| A | ASN227 | |
| A | ASN287 | |
| A | ASN349 | |
| A | ASN389 | |
| A | ASN406 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| A | ASN31 | |
| A | ASN83 | |
| A | ASN286 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21854986, ECO:0007744|PDB:3S98 |
| Chain | Residue | Details |
| A | ASN145 |
