3SCF
Fe(II)-HppE with S-HPP and NO
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016717 | molecular_function | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 0051289 | biological_process | protein homotetramerization |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| A | 1901766 | biological_process | phosphinothricin biosynthetic process |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016717 | molecular_function | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
| B | 0051289 | biological_process | protein homotetramerization |
| B | 0055114 | biological_process | obsolete oxidation-reduction process |
| B | 1901766 | biological_process | phosphinothricin biosynthetic process |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016717 | molecular_function | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| C | 0017000 | biological_process | antibiotic biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051213 | molecular_function | dioxygenase activity |
| C | 0051289 | biological_process | protein homotetramerization |
| C | 0055114 | biological_process | obsolete oxidation-reduction process |
| C | 1901766 | biological_process | phosphinothricin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE2 A 201 |
| Chain | Residue |
| A | HIS138 |
| A | GLU142 |
| A | HIS180 |
| A | S0H205 |
| A | NO209 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE2 B 202 |
| Chain | Residue |
| B | NO210 |
| B | HIS138 |
| B | GLU142 |
| B | HIS180 |
| B | S0H206 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE2 C 203 |
| Chain | Residue |
| C | HIS138 |
| C | GLU142 |
| C | HIS180 |
| C | S0H207 |
| C | HOH214 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO A 209 |
| Chain | Residue |
| A | HIS138 |
| A | GLU142 |
| A | ASN197 |
| A | FE2201 |
| A | S0H205 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO B 210 |
| Chain | Residue |
| B | HIS138 |
| B | GLU142 |
| B | ASN197 |
| B | FE2202 |
| B | S0H206 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE S0H A 205 |
| Chain | Residue |
| A | TYR103 |
| A | TYR105 |
| A | ASN135 |
| A | HIS138 |
| A | GLU142 |
| A | HIS180 |
| A | FE2201 |
| A | NO209 |
| B | LYS23 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE S0H B 206 |
| Chain | Residue |
| A | LYS23 |
| B | ARG97 |
| B | TYR103 |
| B | TYR105 |
| B | ASN135 |
| B | HIS138 |
| B | GLU142 |
| B | HIS180 |
| B | PHE182 |
| B | FE2202 |
| B | HOH209 |
| B | NO210 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE S0H C 207 |
| Chain | Residue |
| C | LYS23 |
| C | ARG97 |
| C | TYR105 |
| C | ASN135 |
| C | HIS138 |
| C | GLU142 |
| C | HIS180 |
| C | FE2203 |
| C | HOH214 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 199 |
| Chain | Residue |
| A | ARG90 |
| A | LYS192 |
| B | GLU148 |
| B | GLY149 |
| B | THR168 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 199 |
| Chain | Residue |
| C | ARG90 |
| C | GLU148 |
| C | LYS192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 57 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00257 |
| Chain | Residue | Details |
| A | HIS26-ASN45 | |
| B | HIS26-ASN45 | |
| C | HIS26-ASN45 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16186494, ECO:0000269|PubMed:21682308, ECO:0007744|PDB:2BNN, ECO:0007744|PDB:3SCH, ECO:0007744|PDB:4J1W, ECO:0007744|PDB:4J1X |
| Chain | Residue | Details |
| A | LYS23 | |
| B | LYS23 | |
| C | LYS23 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16015285, ECO:0000269|PubMed:16186494, ECO:0000269|PubMed:21682308, ECO:0007744|PDB:1ZZ8, ECO:0007744|PDB:2BNN, ECO:0007744|PDB:3SCG, ECO:0007744|PDB:3SCH, ECO:0007744|PDB:4J1W, ECO:0007744|PDB:4J1X |
| Chain | Residue | Details |
| A | ARG97 | |
| B | ARG97 | |
| C | ARG97 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16015285, ECO:0000269|PubMed:16186494, ECO:0000269|PubMed:21682308, ECO:0007744|PDB:1ZZ8, ECO:0007744|PDB:1ZZB, ECO:0007744|PDB:2BNN, ECO:0007744|PDB:3SCF, ECO:0007744|PDB:3SCG, ECO:0007744|PDB:3SCH, ECO:0007744|PDB:4J1W, ECO:0007744|PDB:4J1X |
| Chain | Residue | Details |
| A | TYR105 | |
| B | TYR105 | |
| C | TYR105 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16015285, ECO:0000269|PubMed:16186494, ECO:0000269|PubMed:21682308, ECO:0007744|PDB:1ZZ7, ECO:0007744|PDB:1ZZ8, ECO:0007744|PDB:1ZZB, ECO:0007744|PDB:2BNN, ECO:0007744|PDB:3SCF, ECO:0007744|PDB:3SCG, ECO:0007744|PDB:3SCH, ECO:0007744|PDB:4J1W, ECO:0007744|PDB:4J1X |
| Chain | Residue | Details |
| A | ASN135 | |
| B | ASN135 | |
| C | ASN135 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16015285, ECO:0000269|PubMed:16186494, ECO:0000269|PubMed:21682308, ECO:0007744|PDB:1ZZ7, ECO:0007744|PDB:1ZZ8, ECO:0007744|PDB:1ZZ9, ECO:0007744|PDB:2BNM, ECO:0007744|PDB:2BNN, ECO:0007744|PDB:2BNO, ECO:0007744|PDB:3SCF, ECO:0007744|PDB:3SCG, ECO:0007744|PDB:4J1W, ECO:0007744|PDB:4J1X |
| Chain | Residue | Details |
| A | HIS138 | |
| A | HIS180 | |
| B | HIS138 | |
| B | HIS180 | |
| C | HIS138 | |
| C | HIS180 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16015285, ECO:0000269|PubMed:16186494, ECO:0000269|PubMed:21682308, ECO:0007744|PDB:1ZZ7, ECO:0007744|PDB:1ZZ8, ECO:0007744|PDB:1ZZB, ECO:0007744|PDB:2BNN, ECO:0007744|PDB:3SCF, ECO:0007744|PDB:3SCG, ECO:0007744|PDB:3SCH, ECO:0007744|PDB:4J1W |
| Chain | Residue | Details |
| A | GLU142 | |
| B | GLU142 | |
| C | GLU142 |
